The Ambiguous Salivary Myoepithelial Cells

Salivary gland neoplasms present with a diverse histological pattern which is mainly because of the presence of specialized myoepithelial cells (MECs). These are contractile epithelial cells with smooth muscle like properties. They have been also noticed in mammary glands, lacrimal glands, prostate gland, and the sweat glands and have varied functions. MECs play an important role in the histogenesis of many salivary gland tumors. Knowledge of MECs leads to a better understanding of the histological diversity of salivary gland neoplasms. This article reviews the physiology, histology, identification and role of these cells in salivary gland pathology.