Rhodium(III)-catalyzed C7-position C-H Alkenylation and Alkynylation of Indolines

Overview

Journal Chem Commun (Camb)

Publisher Royal Society of Chemistry

Specialty Chemistry

Date 2015 Jan 9

PMID 25567368

Citations 8

Authors

Xiao-Fei Yang

Xu-Hong Hu

Chao Feng

Teck-Peng Loh

Affiliations

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Abstract

A Rh(III)-catalyzed regioselective C-H alkenylation and alkynylation of indolines is described. This protocol relies on the use of a removable pyridinyl directing group to access valuable C-7 functionalized indoline scaffolds with ample substrate scope and broad functional group tolerance.

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