» Articles » PMID: 25563998

Pancreas Transplant Alone

Overview
Specialty General Surgery
Date 2015 Jan 8
PMID 25563998
Citations 8
Authors
Affiliations
Soon will be listed here.
Abstract

Purpose Of Review: The present article aims to review the current state of diabetes, including its treatment options, and highlight current issues in pancreas transplantation.

Recent Findings: Compared with other areas of transplantation, pancreas transplant/transplantation alone in the absence of kidney disease remains a relatively small field. As a consequence, reported new research articles are few in number, and often data regarding pancreas transplant/transplantation alone are mixed in with simultaneous kidney-pancreas and pancreas after kidney transplantation, which are covered separately. The prevalence of diabetes is reaching epidemic levels and continues to increase. New developments in diabetes care include the bionic pancreas and immunotherapy. Persistent efforts at gene and stem cell therapies are ongoing. Pancreas transplantation outcomes are improving, yet numbers are declining, even though pancreas transplantation still offers the most optimal glycemic control.

Summary: Pancreas transplantation has improving outcomes but stands in competition with other diabetes management options.

Citing Articles

Donor after circulatory death in pancreas transplantation: a scoping review of the literature.

Chassot M, Scheen M, Wassmer C, Compagnon P, Peloso A, Haidar F Front Transplant. 2025; 4:1517354.

PMID: 40071060 PMC: 11893597. DOI: 10.3389/frtra.2025.1517354.


Experience from 100 consecutive pancreas transplants amidst low national transplant activity: a retrospective study at a single center in Korea.

Ryu J, Yang K, Horneland R, Ju S, Choi B Clin Transplant Res. 2024; 38(3):203-211.

PMID: 39344697 PMC: 11464153. DOI: 10.4285/ctr.24.0033.


Local Postoperative Graft Inflammation in Pancreas Transplant Patients With Early Graft Thrombosis.

Rydenfelt K, Kjosen G, Horneland R, Ludviksen J, Jenssen T, Line P Transplant Direct. 2023; 10(1):e1567.

PMID: 38094132 PMC: 10715763. DOI: 10.1097/TXD.0000000000001567.


Pancreas Transplant Alone in the USA, Where Do We Stand?.

Moein M, Papa S, Bahreini A, Saidi R World J Surg. 2023; 47(9):2250-2258.

PMID: 37258778 DOI: 10.1007/s00268-023-07062-w.


Thromboinflammatory response is increased in pancreas transplant alone versus simultaneous pancreas-kidney transplantation and early pancreas graft thrombosis is associated with complement activation.

Rydenfelt K, Kjosen G, Horneland R, Ludviksen J, Jenssen T, Line P Front Immunol. 2023; 14:1044444.

PMID: 37063904 PMC: 10090504. DOI: 10.3389/fimmu.2023.1044444.