» Articles » PMID: 25562731

Cronobacter Sakazakii: Stress Survival and Virulence Potential in an Opportunistic Foodborne Pathogen

Overview
Journal Gut Microbes
Date 2015 Jan 7
PMID 25562731
Citations 21
Authors
Affiliations
Soon will be listed here.
Abstract

A characteristic feature of the opportunistic foodborne pathogen Cronobacter sakazakii is its ability to survive in extremely arid environments, such as powdered infant formula, making it a dangerous opportunistic pathogen of individuals of all age groups, especially infants and neonates. Herein, we provide a brief overview of the pathogen; clinical manifestations, environmental reservoirs and our current understanding of stress response mechanisms and virulence factors which allow it to cause disease.

Citing Articles

2'-Fucosyllactose as a prebiotic modulates the probiotic responses of .

Du J, Yang H Curr Res Food Sci. 2025; 10:100975.

PMID: 39906504 PMC: 11791163. DOI: 10.1016/j.crfs.2025.100975.


Intracellular Survival and Pathogenicity Modulation of Lon, CpxR, and RfaL Mutants Used as Live Bacterial Vectors under Abiotic Stress, Unveiling the Link between Stress Response and Virulence in Epithelial Cells.

Kirthika P, Senevirathne A, Park S, Aganja R, Kim I, Tae H Int J Mol Sci. 2024; 25(16).

PMID: 39201742 PMC: 11354574. DOI: 10.3390/ijms25169056.


Effects of Gene on Adhesion/Invasion and Virulence of and Its Molecular Mechanism.

Fan Y, Li P, Zhu D, Zhao C, Jiao J, Ji X Foods. 2023; 12(13).

PMID: 37444309 PMC: 10340232. DOI: 10.3390/foods12132572.


White common bean extract remodels the gut microbiota and ameliorates type 2 diabetes and its complications: A randomized double-blinded placebo-controlled trial.

Feng Y, Zhu J, Wang Q, Cao H, He F, Guan Y Front Endocrinol (Lausanne). 2022; 13:999715.

PMID: 36303868 PMC: 9594986. DOI: 10.3389/fendo.2022.999715.


Comparison of Essential Oil Chemical Compounds and Their Antibacterial Activity against .

Guo X, Hao Y, Zhang W, Xia F, Bai H, Li H Molecules. 2022; 27(19).

PMID: 36235238 PMC: 9571376. DOI: 10.3390/molecules27196702.


References
1.
Wood J, Bremer E, Csonka L, Kraemer R, Poolman B, van der Heide T . Osmosensing and osmoregulatory compatible solute accumulation by bacteria. Comp Biochem Physiol A Mol Integr Physiol. 2002; 130(3):437-60. DOI: 10.1016/s1095-6433(01)00442-1. View

2.
Iversen C, Waddington M, On S, Forsythe S . Identification and phylogeny of Enterobacter sakazakii relative to Enterobacter and Citrobacter Species. J Clin Microbiol. 2004; 42(11):5368-70. PMC: 525200. DOI: 10.1128/JCM.42.11.5368-5370.2004. View

3.
Zuber S, Boissin-Delaporte C, Michot L, Iversen C, Diep B, Brussow H . Decreasing Enterobacter sakazakii (Cronobacter spp.) food contamination level with bacteriophages: prospects and problems. Microb Biotechnol. 2011; 1(6):532-43. PMC: 3815295. DOI: 10.1111/j.1751-7915.2008.00058.x. View

4.
Stock I, Wiedemann B . Natural antibiotic susceptibility of Enterobacter amnigenus, Enterobacter cancerogenus, Enterobacter gergoviae and Enterobacter sakazakii strains. Clin Microbiol Infect. 2002; 8(9):564-78. DOI: 10.1046/j.1469-0691.2002.00413.x. View

5.
Joseph S, Desai P, Ji Y, Cummings C, Shih R, Degoricija L . Comparative analysis of genome sequences covering the seven cronobacter species. PLoS One. 2012; 7(11):e49455. PMC: 3500316. DOI: 10.1371/journal.pone.0049455. View