A Highly Selective and Sensitive Turn-On Fluorescent Chemosensor Based on Rhodamine 6G for Iron(III)

Overview

Journal ChemistryOpen

Specialty Chemistry

Date 2015 Jan 6

PMID 25558445

Citations 2

Authors

Zhi-Qiang Hu

Ying-Ying Gu

Wen-Zhou Hu

Lei-Li Sun

Jiang-Hua Zhu

Yi Jiang

Affiliations

Soon will be listed here.

Abstract

Recently, more and more rhodamine derivatives have been used as fluorophores to construct sensors due to their excellent spectroscopic properties. A rhodamine-based fluorescent and colorimetric Fe(3+) chemosensor 3',6'-bis(ethylamino)-2-acetoxyl-2',7'-dimethyl-spiro[1H-isoindole-1,9'-[9H]xanthen]-3(2H)-one (RAE) was designed and synthesized. Upon the addition of Fe(3+), the dramatic enhancement of both fluorescence and absorbance intensity, as well as the color change of the solution, could be observed. The detection limit of RAE for Fe(3+) was around 7.98 ppb. Common coexistent metal ions showed little or no interference in the detection of Fe(3+). Moreover, the addition of CN(-) could quench the fluorescence of the acetonitrile solution of RAE and Fe(3+), indicating the regeneration of the chemosensor RAE. The robust nature of the sensor was shown by the detection of Fe(3+) even after repeated rounds of quenching. As iron is a ubiquitous metal in cells and plays vital roles in many biological processes, this chemosensor could be developed to have applications in biological studies.

Citing Articles

Remarkably selective biocompatible turn-on fluorescent probe for detection of Fe in human blood samples and cells.

V H V, Saxena M, R G, Latiyan S, Jain S RSC Adv. 2022; 9(47):27439-27448.

PMID: 35529189 PMC: 9070666. DOI: 10.1039/c9ra05256a.

Highly Sensitive and Selective Turn-on Fluorescent Probe for Hg Based on Rhodamine 6G-Thiourea Conjugate.

Ding Y, Gong H, Wang K J Fluoresc. 2017; 27(3):1095-1099.

PMID: 28233249 DOI: 10.1007/s10895-017-2044-z.

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