Broca's Area - Thalamic Connectivity

Overview

Journal Brain Lang

Publisher Elsevier

Specialties Neurology
Otorhinolaryngology
Psychiatry

Date 2015 Jan 3

PMID 25555132

Citations 20

Authors

Anastasia A Bohsali

William Triplett

Atchar Sudhyadhom

Joseph M Gullett

Keith McGregor

David B FitzGerald

Thomas Mareci

Keith White

Bruce Crosson

Affiliations

Soon will be listed here.

Abstract

Broca's area is crucially involved in language processing. The sub-regions of Broca's area (pars triangularis, pars opercularis) presumably are connected via corticocortical pathways. However, growing evidence suggests that the thalamus may also be involved in language and share some of the linguistic functions supported by Broca's area. Functional connectivity is thought to be achieved via corticothalamic/thalamocortical white matter pathways. Our study investigates structural connectivity between Broca's area and the thalamus, specifically ventral anterior nucleus and pulvinar. We demonstrate that Broca's area shares direct connections with these thalamic nuclei and suggest a local Broca's area-thalamus network potentially involved in linguistic processing. Thalamic connectivity with Broca's area may serve to selectively recruit cortical regions storing multimodal features of lexical items and to bind them together during lexical-semantic processing. In addition, Broca's area-thalamic circuitry may enable cortico-thalamo-cortical information transfer and modulation between BA 44 and 45 during language comprehension and production.

Citing Articles

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