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Suboptimal Effect of Daptomycin in the Treatment of Bacteremias

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Journal South Med J
Date 1989 Nov 1
PMID 2554510
Citations 11
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Abstract

We have reported two cases involving bacteremic patients who failed to respond adequately to the investigational agent daptomycin. Despite apparent sensitivity of the organisms, therapy was unsuccessful in both patients using the recommended dosage. The sponsor of daptomycin is currently reevaluating the recommendation and may be revising their dosage guidelines in the future.

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