Dermatosis Associated with Menopause

Overview

Journal J Midlife Health

Date 2014 Dec 26

PMID 25540566

Citations 11

Authors

Pragya A Nair

Affiliations

Soon will be listed here.

Abstract

Menopause is defined as permanent irreversible cessation of menses brought by decline in ovarian follicular activity. Hormonal alteration results in various physical, psychological, and sexual changes in menopausal women. Associated dermatological problems can be classified as physiological changes, age-related changes, changes due to estrogen deficiency and due to hormone replacement therapy. Dermatosis seen due to estrogen deficiency includes Atrophic Vulvovaginitis, Vulvar Lichen Sclerosus, Dyaesthetic Vulvodynia, Hirsutism, Alopecia, Menopausal Flushing, Keratoderma Climactericum, Vulvovaginal Candidiasis. Dermatologists and gynecologists need to be familiar with the problems of menopausal women, as with increase in life expectancy, women passing through this phase is rising.

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References

Scheinfeld N . Obesity and dermatology. Clin Dermatol. 2004; 22(4):303-9. DOI: 10.1016/j.clindermatol.2004.01.001. View

Chen W, Yang C, Todorova A, Al Khuzaei S, Chiu H, Worret W . Hair loss in elderly women. Eur J Dermatol. 2010; 20(2):145-51. DOI: 10.1684/ejd.2010.0828. View

Georgala S, Katoulis A, Befon A, Danopoulou I, Georgala C . Treatment of postmenopausal frontal fibrosing alopecia with oral dutasteride. J Am Acad Dermatol. 2009; 61(1):157-8. DOI: 10.1016/j.jaad.2008.12.026. View

Blumeyer A, Tosti A, Messenger A, Reygagne P, Del Marmol V, Spuls P . Evidence-based (S3) guideline for the treatment of androgenetic alopecia in women and in men. J Dtsch Dermatol Ges. 2011; 9 Suppl 6:S1-57. DOI: 10.1111/j.1610-0379.2011.07802.x. View

Sinclair R, Wewerinke M, Jolley D . Treatment of female pattern hair loss with oral antiandrogens. Br J Dermatol. 2005; 152(3):466-73. DOI: 10.1111/j.1365-2133.2005.06218.x. View

Casper R, Yen S . Neuroendocrinology of menopausal flushes: an hypothesis of flush mechanism. Clin Endocrinol (Oxf). 1985; 22(3):293-312. DOI: 10.1111/j.1365-2265.1985.tb03243.x. View

Hoffmann R, Niiyama S, Huth A, Kissling S, Happle R . 17alpha-estradiol induces aromatase activity in intact human anagen hair follicles ex vivo. Exp Dermatol. 2002; 11(4):376-80. DOI: 10.1034/j.1600-0625.2002.110413.x. View

Mulley G, Mitchell J . Menopausal flushing: does oestrogen therapy make sense?. Lancet. 1976; 1(7974):1397-9. DOI: 10.1016/s0140-6736(76)93040-3. View

Hassa H, Tanir H, Tekin B, Senses T, Oge T, Mutlu F . Possible factors affecting the age at menopause among women in the central anatolian region of Turkey. Clin Exp Obstet Gynecol. 2006; 33(1):59-60. View

10.

Meeta , Digumarti L, Agarwal N, Vaze N, Shah R, Malik S . Clinical practice guidelines on menopause: An executive summary and recommendations. J Midlife Health. 2013; 4(2):77-106. PMC: 3785158. DOI: 10.4103/0976-7800.115290. View

11.

Calleja-Agius J, Brincat M . Urogenital atrophy. Climacteric. 2009; 12(4):279-85. DOI: 10.1080/13697130902814751. View

12.

Imbert I, Botto J, Farra C, Domloge N . Modulation of telomere binding proteins: a future area of research for skin protection and anti-aging target. J Cosmet Dermatol. 2012; 11(2):162-6. DOI: 10.1111/j.1473-2165.2012.00611.x. View

13.

Tasker G, Wojnarowska F . Lichen sclerosus. Clin Exp Dermatol. 2003; 28(2):128-33. DOI: 10.1046/j.1365-2230.2003.01211.x. View

14.

Messina M, Hughes C . Efficacy of soyfoods and soybean isoflavone supplements for alleviating menopausal symptoms is positively related to initial hot flush frequency. J Med Food. 2003; 6(1):1-11. DOI: 10.1089/109662003765184697. View

15.

Graham-Brown R . Dermatologic problems of the menopause. Clin Dermatol. 1997; 15(1):143-5. DOI: 10.1016/s0738-081x(96)00116-2. View

16.

Powell J, Wojnarowska F, Winsey S, Marren P, Welsh K . Lichen sclerosus premenarche: autoimmunity and immunogenetics. Br J Dermatol. 2000; 142(3):481-4. DOI: 10.1046/j.1365-2133.2000.03360.x. View

17.

Nissan H, Lu J, Booth N, Yamamura H, Farnsworth N, Wang Z . A red clover (Trifolium pratense) phase II clinical extract possesses opiate activity. J Ethnopharmacol. 2007; 112(1):207-10. DOI: 10.1016/j.jep.2007.02.006. View

18.

Cheema D, Coomarasamy A, El-Toukhy T . Non-hormonal therapy of post-menopausal vasomotor symptoms: a structured evidence-based review. Arch Gynecol Obstet. 2007; 276(5):463-9. DOI: 10.1007/s00404-007-0390-9. View

19.

Braunstein G . Management of female sexual dysfunction in postmenopausal women by testosterone administration: safety issues and controversies. J Sex Med. 2007; 4(4 Pt 1):859-66. DOI: 10.1111/j.1743-6109.2007.00516.x. View

20.

Sander C, Ali I, Dean D, Thiele J, Wojnarowska F . Oxidative stress is implicated in the pathogenesis of lichen sclerosus. Br J Dermatol. 2004; 151(3):627-35. DOI: 10.1111/j.1365-2133.2004.06142.x. View