Ebola Virus Infection: What Should Be Known?

Overview

Journal N Am J Med Sci

Specialty General Medicine

Date 2014 Dec 24

PMID 25535601

Citations 7

Authors

Viroj Wiwanitkit

Affiliations

Soon will be listed here.

Abstract

Ebola virus infection is the present global consideration. This deadly virus can result in a deadly acute febrile hemorrhagic illness. The patient can have several clinical manifestations. As a new emerging infection, the knowledge on this infection is extremely limited. The interesting issues to be discussed include a) the atypical clinical presentation, b) new diagnostic tool, c) new treatment, and d) disease prevention. Those topics will be discussed in this special review.

Citing Articles

Evaluation of viral haemorrhagic fever surveillance system with focus on Ebola virus disease, Bawku municipality- Upper East Region, Ghana, 2011-2015.

Broni F, Larbi J, Afari E, Nyarko K, Ameme D, Kenu E Ghana Med J. 2021; 54(2 Suppl):18-25.

PMID: 33536664 PMC: 7837345. DOI: 10.4314/gmj.v54i2s.4.

Ebola Hemorrhagic Shock Syndrome-on-a-Chip.

Junaid A, Tang H, van Reeuwijk A, Abouleila Y, Wuelfroth P, van Duinen V iScience. 2019; 23(1):100765.

PMID: 31887664 PMC: 6941864. DOI: 10.1016/j.isci.2019.100765.

Ebola virus: A global public health menace: A narrative review.

Hasan S, Ahmad S, Masood R, Saeed S J Family Med Prim Care. 2019; 8(7):2189-2201.

PMID: 31463229 PMC: 6691429. DOI: 10.4103/jfmpc.jfmpc_297_19.

The Understanding of Ebola Virus Disease (EVD) Among Medical Practitioners of Karachi, Pakistan.

Shakeel S, Iffat W, Naqvi A, Ahmed F, Usmani S, Mazhar M Trop Med Infect Dis. 2018; 2(2).

PMID: 30270875 PMC: 6082072. DOI: 10.3390/tropicalmed2020016.

Ebola and pregnancy.

Wiwanitkit V Obstet Med. 2016; 9(1):50.

PMID: 27512492 PMC: 4950435. DOI: 10.1177/1753495X15617581.

References

Osterholm M, Moore K, Gostin L . Public health in the age of ebola in West Africa. JAMA Intern Med. 2014; 175(1):7-8. DOI: 10.1001/jamainternmed.2014.6235. View

Qiu X, Wong G, Audet J, Bello A, Fernando L, Alimonti J . Reversion of advanced Ebola virus disease in nonhuman primates with ZMapp. Nature. 2014; 514(7520):47-53. PMC: 4214273. DOI: 10.1038/nature13777. View

Mandl K . Ebola in the United States: EHRs as a public health tool at the point of care. JAMA. 2014; 312(23):2499-500. DOI: 10.1001/jama.2014.15064. View

Yang Y, Bai L, Hu K, Yang Z, Hu J, Wang J . [Multiplex real-time PCR method for rapid detection of Marburg virus and Ebola virus]. Zhonghua Shi Yan He Lin Chuang Bing Du Xue Za Zhi. 2012; 26(4):313-5. View

Gunther S, Feldmann H, Geisbert T, Hensley L, Rollin P, Nichol S . Management of accidental exposure to Ebola virus in the biosafety level 4 laboratory, Hamburg, Germany. J Infect Dis. 2011; 204 Suppl 3:S785-90. DOI: 10.1093/infdis/jir298. View

Leroy E, Baize S, Volchkov V, Fisher-Hoch S, Georges-Courbot M, Capron M . Human asymptomatic Ebola infection and strong inflammatory response. Lancet. 2000; 355(9222):2210-5. DOI: 10.1016/s0140-6736(00)02405-3. View

Hill C, Burd E, Kraft C, Ryan E, Duncan A, Winkler A . Laboratory test support for Ebola patients within a high-containment facility. Lab Med. 2014; 45(3):e109-11. DOI: 10.1309/LMTMW3VVN20HIFS. View

Ray R, Basu A, Steele R, Beyene A, McHowat J, Meyer K . Ebola virus glycoprotein-mediated anoikis of primary human cardiac microvascular endothelial cells. Virology. 2004; 321(2):181-8. DOI: 10.1016/j.virol.2003.12.014. View

Larsen T, Stevens E, Davis K, Geisbert J, Daddario-DiCaprio K, Jahrling P . Pathologic findings associated with delayed death in nonhuman primates experimentally infected with Zaire Ebola virus. J Infect Dis. 2007; 196 Suppl 2:S323-8. DOI: 10.1086/520589. View

10.

Baskerville A, Fisher-Hoch S, Neild G, Dowsett A . Ultrastructural pathology of experimental Ebola haemorrhagic fever virus infection. J Pathol. 1985; 147(3):199-209. DOI: 10.1002/path.1711470308. View

11.

Smither S, Eastaugh L, Steward J, Nelson M, Lenk R, Lever M . Post-exposure efficacy of oral T-705 (Favipiravir) against inhalational Ebola virus infection in a mouse model. Antiviral Res. 2014; 104:153-5. DOI: 10.1016/j.antiviral.2014.01.012. View

12.

Vladyko A, Zaitseva V, TROFIMOV N, Shkolina T, Scheslenok E, Boshchenko I . [False-positive reactions in laboratory diagnosis of Lassa, Marburg, and Ebola viral hemorrhagic fevers and AIDS]. Vopr Virusol. 1997; 42(2):66-70. View

13.

Bowick G, McAuley A . Meta-analysis of high-throughput datasets reveals cellular responses following hemorrhagic fever virus infection. Viruses. 2011; 3(5):613-9. PMC: 3185756. DOI: 10.3390/v3050613. View

14.

Rollin P, Bausch D, Sanchez A . Blood chemistry measurements and D-Dimer levels associated with fatal and nonfatal outcomes in humans infected with Sudan Ebola virus. J Infect Dis. 2007; 196 Suppl 2:S364-71. DOI: 10.1086/520613. View

15.

Huang Y, Wei H, Wang Y, Shi Z, Raoul H, Yuan Z . Rapid detection of filoviruses by real-time TaqMan polymerase chain reaction assays. Virol Sin. 2012; 27(5):273-7. PMC: 8218046. DOI: 10.1007/s12250-012-3252-y. View

16.

Garrison A, Giomarelli B, Lear-Rooney C, Saucedo C, Yellayi S, Krumpe L . The cyanobacterial lectin scytovirin displays potent in vitro and in vivo activity against Zaire Ebola virus. Antiviral Res. 2014; 112:1-7. PMC: 4258435. DOI: 10.1016/j.antiviral.2014.09.012. View

17.

van der Waals F, Pomeroy K, Goudsmit J, Asher D, Gajdusek D . Hemorrhagic fever virus infections in an isolated rainforest area of central Liberia. Limitations of the indirect immunofluorescence slide test for antibody screening in Africa. Trop Geogr Med. 1986; 38(3):209-14. View

18.

Cohen J, Kupferschmidt K . Infectious Diseases. Ebola vaccine trials raise ethical issues. Science. 2014; 346(6207):289-90. DOI: 10.1126/science.346.6207.289. View

19.

Leroy E, Baize S, Debre P, Mavoungou E . Early immune responses accompanying human asymptomatic Ebola infections. Clin Exp Immunol. 2001; 124(3):453-60. PMC: 1906073. DOI: 10.1046/j.1365-2249.2001.01517.x. View

20.

Kortepeter M, Lawler J, Honko A, Bray M, Johnson J, Purcell B . Real-time monitoring of cardiovascular function in rhesus macaques infected with Zaire ebolavirus. J Infect Dis. 2011; 204 Suppl 3:S1000-10. DOI: 10.1093/infdis/jir337. View