Primary Hyperoxalurias: Diagnosis and Treatment

Overview

Journal Pediatr Nephrol

Specialties Nephrology
Pediatrics

Date 2014 Dec 19

PMID 25519509

Citations 19

Authors

Efrat Ben-Shalom

Yaacov Frishberg

Affiliations

Soon will be listed here.

Abstract

Primary hyperoxalurias (PH) comprise a group of three distinct metabolic diseases caused by derangement of glyoxylate metabolism in the liver. Recent years have seen advances in several aspects of PH research. This paper reviews current knowledge of the genetic and biochemical basis of PH, the specific epidemiology and clinical presentation of each type, and therapeutic approaches in different disease stages. Potential future specific therapies are discussed.

Citing Articles

Bone health in children with primary hyperoxaluria type 1 following liver and kidney transplantation.

Buscher R, Pape L, Buscher A Front Pediatr. 2024; 12:1353880.

PMID: 38455394 PMC: 10917879. DOI: 10.3389/fped.2024.1353880.

Boussetta A, Fatnassi R, Jellouli M, Maamouri R, Mrad R, Gargah T Tunis Med. 2024; 101(7):626-630.

PMID: 38445424 PMC: 11217970.

Long-term outcomes after pre-emptive liver transplantation in primary hyperoxaluria type 1.

Shasha-Lavsky H, Avni A, Paz Z, Kalfon L, Dror A, Yakir O Pediatr Nephrol. 2022; 38(6):1811-1820.

PMID: 36449101 DOI: 10.1007/s00467-022-05803-y.

Primary hyperoxaluria: the pediatric nephrologist's point of view.

Ben-Shalom E, Garrelfs S, Groothoff J Clin Kidney J. 2022; 15(Suppl 1):i23-i28.

PMID: 35592624 PMC: 9113416. DOI: 10.1093/ckj/sfab231.

Clinical and economic impact of primary hyperoxaluria: a retrospective claims analysis.

Mucha L, Hoppe B, Silber A, Wang Z, Miyasato G, Skaar J J Manag Care Spec Pharm. 2022; 28(3):316-323.

PMID: 35199581 PMC: 10373026. DOI: 10.18553/jmcp.2022.28.3.316.

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