Extensive Presentation of Central Ossifying Fibroma Treated with Conservative Surgical Excision

Overview

Journal Case Rep Dent

Publisher Wiley

Specialty Dentistry

Date 2014 Dec 16

PMID 25506435

Authors

Matheus Henrique Lopes Dominguete

Alexandre Augusto Sarto Dominguette

Bruno Henrique Matos

Paulo Roberto Dominguete

Jorge Esquiche Leon

Lucinei Roberto Oliveira

Affiliations

Soon will be listed here.

Abstract

Central ossifying fibroma is a benign slow-growing tumor of mesenchymal origin and it tends to occur in the second and third decades of life, with predilection for women and for the mandibular premolar and molar areas. Clinically, it is a large asymptomatic tumor of aggressive appearance, with possible tooth displacement. Occasionally treated by curettage enucleation, this conservative surgical excision is showing a recurrence rate extremely low. The objective of this study was to report a case of a 44-year-old woman, presenting a very large ossifying fibroma in the mandible, which was successfully treated with curettage, and to conduct a brief literature review of this lesion, focusing on the histology, clinical behavior, and management of these uncommon lesions.

References

Nakagawa K, Takasato Y, Ito Y, Yamada K . Ossifying fibroma involving the paranasal sinuses, orbit, and anterior cranial fossa: case report. Neurosurgery. 1995; 36(6):1192-5. DOI: 10.1227/00006123-199506000-00021. View

Bertolini F, Caradonna L, Bianchi B, Sesenna E . Multiple ossifying fibromas of the jaws: a case report. J Oral Maxillofac Surg. 2002; 60(2):225-9. DOI: 10.1053/joms.2002.29832. View

Matsuzaka K, Shimono M, Uchiyama T, Noma H, Inoue T . Lesions related to the formation of bone, cartilage or cementum arising in the oral area: a statistical study and review of the literature. Bull Tokyo Dent Coll. 2002; 43(3):173-80. DOI: 10.2209/tdcpublication.43.173. View

Chang C, Hung H, Yu-Fong Chang J, Yu C, Wang Y, Liu B . Central ossifying fibroma: a clinicopathologic study of 28 cases. J Formos Med Assoc. 2008; 107(4):288-94. DOI: 10.1016/S0929-6646(08)60089-3. View

Sciubba J, Younai F . Ossifying fibroma of the mandible and maxilla: review of 18 cases. J Oral Pathol Med. 1989; 18(6):315-21. DOI: 10.1111/j.1600-0714.1989.tb01559.x. View

Tortorici S, Buzzanca M, Burruano F, Difalco P . Juvenile central ossifying fibroma of the mandible: a case report. J Pediatr Surg. 2010; 45(10):e1-4. DOI: 10.1016/j.jpedsurg.2010.06.025. View

Delilbasi C, Sencimen M, Okcu K . A large mass in the maxilla: clinical features and differential diagnosis. J Can Dent Assoc. 2009; 75(4):269, 272-3. View

Slootweg P . Lesions of the jaws. Histopathology. 2008; 54(4):401-18. DOI: 10.1111/j.1365-2559.2008.03097.x. View

Triantafillidou K, Venetis G, Karakinaris G, Iordanidis F . Ossifying fibroma of the jaws: a clinical study of 14 cases and review of the literature. Oral Surg Oral Med Oral Pathol Oral Radiol. 2012; 114(2):193-9. DOI: 10.1016/j.tripleo.2011.07.033. View

10.

Zama M, Gallo S, Santecchia L, Bertozzi E, De Stefano C . Juvenile active ossifying fibroma with massive involvement of the mandible. Plast Reconstr Surg. 2004; 113(3):970-4. DOI: 10.1097/01.prs.0000105629.56850.aa. View

11.

Martin-Granizo R, Falahat F . Cemento-ossifying fibroma of the upper gingivae. Otolaryngol Head Neck Surg. 2000; 122(5):775. DOI: 10.1016/S0194-5998(00)70216-6. View

12.

Gurol M, Uckan S, Guler N, Yatmaz P . Surgical and reconstructive treatment of a large ossifying fibroma of the mandible in a retrognathic patient. J Oral Maxillofac Surg. 2001; 59(9):1097-100. DOI: 10.1053/joms.2001.25858. View

13.

Liu Y, Wang H, You M, Yang Z, Miao J, Shimizutani K . Ossifying fibromas of the jaw bone: 20 cases. Dentomaxillofac Radiol. 2010; 39(1):57-63. PMC: 3520406. DOI: 10.1259/dmfr/96330046. View

14.

Brannon R, Fowler C . Benign fibro-osseous lesions: a review of current concepts. Adv Anat Pathol. 2001; 8(3):126-43. DOI: 10.1097/00125480-200105000-00002. View

15.

Kreutziger K, Weiss L . Cementifying fibroma: resection of recurrent mandibular lesion with microsurgical preservation of inferior alveolar nerve and immediate reconstruction. South Med J. 1994; 87(6):653-8. DOI: 10.1097/00007611-199406000-00015. View

16.

Ribeiro A, Carlos R, Diaz K, Gouvea A, Vargas P . Bilateral central ossifying fibroma affecting the mandible: report of an uncommon case and critical review of the literature. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2011; 111(2):e21-6. DOI: 10.1016/j.tripleo.2010.10.024. View