Near-infrared Upconversion Nanoparticles for Bio-applications

Overview

Journal Mater Sci Eng C Mater Biol Appl

Publisher Elsevier

Specialties Biomedical Engineering
Biotechnology

Date 2014 Dec 11

PMID 25491873

Citations 10

Authors

Qing Qing Dou

Hong Chen Guo

Enyi Ye

Affiliations

Soon will be listed here.

Abstract

Upconversion nanoparticles (UCNs) attract intensive attentions in biomedical applications. They have shown great potential in bioimaging, biomolecule detection, drug delivery, photodynamic therapy and cellular molecules interactions. Due to the anti-Stokes optical property and NIR excitation, UCNs overcome the drawbacks encountered in conventional luminescent biomarkers. High signal to noise ratio, low cytotoxicity and stable high throughput results are obtained using UCNs as luminescent labels or light triggers in biomedical applications. In this review article, the reason for choosing UCNs as biomedical agents, the progress of the UCNs development and case studies of their biomedical applications will be discussed.

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