Serum Immunoglobulin A Response to Norwalk Virus Infection

Overview

Journal J Clin Microbiol

Specialty Microbiology

Date 1989 Jun 1

PMID 2546980

Citations 14

Authors

D D Erdman

G W Gary

L J Anderson

Affiliations

Soon will be listed here.

Abstract

We describe the serum immunoglobulin A (IgA) antibody response to Norwalk virus infection in human volunteers and compare it with previously described IgM and total antibody responses. Whereas specific IgA and IgM peak within 2 weeks after onset of symptoms, titers of total blocking antibody continue to rise, implying mediation by IgG antibody.

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References

Parrino T, Schreiber D, Trier J, Kapikian A, Blacklow N . Clinical immunity in acute gastroenteritis caused by Norwalk agent. N Engl J Med. 1977; 297(2):86-9. DOI: 10.1056/NEJM197707142970204. View

Blacklow N, Cukor G, Bedigian M, Echeverria P, Greenberg H, Schreiber D . Immune response and prevalence of antibody to Norwalk enteritis virus as determined by radioimmunoassay. J Clin Microbiol. 1979; 10(6):903-9. PMC: 273291. DOI: 10.1128/jcm.10.6.903-909.1979. View

Kaplan J, Gary G, Baron R, Singh N, Schonberger L, Feldman R . Epidemiology of Norwalk gastroenteritis and the role of Norwalk virus in outbreaks of acute nonbacterial gastroenteritis. Ann Intern Med. 1982; 96(6 Pt 1):756-61. DOI: 10.7326/0003-4819-96-6-756. View

Cukor G, Nowak N, Blacklow N . Immunoglobulin M responses to the Norwalk virus of gastroenteritis. Infect Immun. 1982; 37(2):463-8. PMC: 347556. DOI: 10.1128/iai.37.2.463-468.1982. View

Erdman D, Gary G, Anderson L . Development and evaluation of an IgM capture enzyme immunoassay for diagnosis of recent Norwalk virus infection. J Virol Methods. 1989; 24(1-2):57-66. DOI: 10.1016/0166-0934(89)90007-4. View