Sendai Virus Infection of Mice with Protein Malnutrition

Overview

Journal J Virol

Publisher American Society for Microbiology

Date 1989 Aug 1

PMID 2545924

Citations 14

Authors

V Pena-Cruz

C S Reiss

K McIntosh

Affiliations

Soon will be listed here.

Abstract

Sendai virus pneumonia was produced in BALB/c mice fed protein-deficient diets in an effort to understand the severity of viral pneumonia in infants in developing countries. Animals on the deficient diet became clinically malnourished, and some aspects of cellular immunity were altered. In protein-deprived animals, the 50% lethal dose of intranasally administered Sendai virus was over 1,000-fold lower, pulmonary virus titers were higher, the infection was prolonged, and lung infection was established at a lower inoculum than in normal animals.

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References

Pocino M, Baute L, Malave I . Calorie restriction modifies the delayed-type hypersensitivity response to the hapten trinitrobenzenesulfonic acid and to hapten-modified syngeneic spleen cells. Cell Immunol. 1987; 109(2):261-71. DOI: 10.1016/0008-8749(87)90310-8. View

Iwai H, Goto Y, Ueda K . Response of athymic nude mice to Sendai virus. Jpn J Exp Med. 1979; 49(2):123-30. View

Pollett M, MacKenzie J, Turner K . The effect of protein-deprivation on the susceptibility to influenza virus infection: a murine model system. Aust J Exp Biol Med Sci. 1979; 57(2):151-60. DOI: 10.1038/icb.1979.16. View

McCance R, WIDDOWSON E . Protein deficiencies and calorie deficiencies. Lancet. 1966; 2(7455):158-9. DOI: 10.1016/s0140-6736(66)92439-1. View

Noonan F, HALLIDAY W . Studies of contact hypersensitivity and tolerance in vivo and in vitro. I. Basic characteristics of the reactions and confirmation of an immune response in tolerant mice. Int Arch Allergy Appl Immunol. 1978; 56(6):523-32. View

Tupasi T, Velmonte M, Sanvictores M, Abraham L, De Leon L, Tan S . Determinants of morbidity and mortality due to acute respiratory infections: implications for intervention. J Infect Dis. 1988; 157(4):615-23. DOI: 10.1093/infdis/157.4.615. View

Kuchroo V, HALLIDAY W . Cellular requirements for the suppression of leucocyte adherence inhibition reactions by serum factors from tumour-bearing mice. Immunology. 1986; 57(4):545-52. PMC: 1453871. View

Doumas B, Watson W, BIGGS H . Albumin standards and the measurement of serum albumin with bromcresol green. Clin Chim Acta. 1971; 31(1):87-96. DOI: 10.1016/0009-8981(71)90365-2. View

Shann F . Etiology of severe pneumonia in children in developing countries. Pediatr Infect Dis. 1986; 5(2):247-52. DOI: 10.1097/00006454-198603000-00017. View

10.

Bell R, Hazell L, Price P . Influence of dietary protein restriction on immune competence. II. Effect on lymphoid tissue. Clin Exp Immunol. 1976; 26(2):314-26. PMC: 1540839. View

11.

KIRSCH R, BROCK J, SAUNDERS S . Experimental protein-calorie malnutrition. Am J Clin Nutr. 1968; 21(8):820-6. DOI: 10.1093/ajcn/21.8.820. View

12.

Prinsloo J, Pretorius P . Body-weights and serum protein values of Bantu children with pneumonia. S Afr Med J. 1966; 40(11):243-4. View

13.

Nunez R, Dugue J, Henriquez C, Villegas A, Nino J, De Gonzales B . Viral and chlamydial etiology of acute infections of the lower respiratory tract in Colombian children. Pediatr Infect Dis J. 1988; 7(1):69-70. DOI: 10.1097/00006454-198801000-00016. View

14.

FLANIGAN C, SPRUNT D . The effect of malnutrition on the susceptibility of the host to viral infection. J Exp Med. 1956; 104(5):687-706. PMC: 2136615. DOI: 10.1084/jem.104.5.687. View