Are Fibrinogen and Complete Blood Count Parameters Predictive in Incarcerated Abdominal Hernia Repair?

Overview

Journal Int Surg

Specialty General Surgery

Date 2014 Dec 2

PMID 25437578

Citations 3

Authors

Sahin Kahramanca

Oskay Kaya

Gulay Ozgehan

Hakan Guzel

Cem Azili

Emre Gokce

Tevfik Kucukpinar

Hakan Kulacoglu

Affiliations

Soon will be listed here.

Abstract

Therapeutic delays in cases of external incarcerated hernias typically result in increasing morbidity, mortality, and health expenditures. We investigated the diagnostic role of blood fibrinogen level, white blood count (WBC), mean platelet volume (MPV), and platelet distribution width (PDW) in patients with incarcerated hernia. Two groups, each containing 100 patients, were studied. Group A underwent elective, and group B underwent incarcerated and urgent external hernia repair. We observed high fibrinogen and WBC levels but low MPV and PDW values for patients in group B. Contrary to our expectations, we found lower MPV and PDW values in the complicated group than in the elective group. The morbidity rate and cost burden were higher in group B, and the results were statistically significant. Early operation should be recommended for patients with incarcerated external hernias if their fibrinogen and WBC levels are high.

Citing Articles

Emergency repair of complicated abdominal wall hernias: WSES guidelines.

De Simone B, Birindelli A, Ansaloni L, Sartelli M, Coccolini F, Di Saverio S Hernia. 2019; 24(2):359-368.

PMID: 31407109 DOI: 10.1007/s10029-019-02021-8.

2017 update of the WSES guidelines for emergency repair of complicated abdominal wall hernias.

Birindelli A, Sartelli M, Di Saverio S, Coccolini F, Ansaloni L, van Ramshorst G World J Emerg Surg. 2017; 12:37.

PMID: 28804507 PMC: 5545868. DOI: 10.1186/s13017-017-0149-y.

IS RDW A PREDICTIVE PARAMETER FOR CUBITAL TUNNEL SYNDROME PATIENTS REQUIRING SURGERY?.

Sarman H, Isik C, Boz M, Boyraz I, Koc B, Turkoglu S Acta Ortop Bras. 2017; 24(4):187-190.

PMID: 28243171 PMC: 5035689. DOI: 10.1590/1413-785220162404156646.

References

Andrews N . Presentation and outcome of strangulated external hernia in a district general hospital. Br J Surg. 1981; 68(5):329-32. DOI: 10.1002/bjs.1800680513. View

Di Napoli M, Singh P . Is plasma fibrinogen useful in evaluating ischemic stroke patients?: why, how, and when. Stroke. 2009; 40(5):1549-52. DOI: 10.1161/STROKEAHA.108.537084. View

Robbins G, Barnard D . Mean platelet volume changes in infection. J Clin Pathol. 1983; 36(11):1320. PMC: 498556. DOI: 10.1136/jcp.36.11.1320-a. View

Patrick C, Lazarchick J . The effect of bacteremia on automated platelet measurements in neonates. Am J Clin Pathol. 1990; 93(3):391-4. DOI: 10.1093/ajcp/93.3.391. View

Slavka G, Perkmann T, Haslacher H, Greisenegger S, Marsik C, Wagner O . Mean platelet volume may represent a predictive parameter for overall vascular mortality and ischemic heart disease. Arterioscler Thromb Vasc Biol. 2011; 31(5):1215-8. DOI: 10.1161/ATVBAHA.110.221788. View

Aydemir H, Piskin N, Akduman D, Kokturk F, Aktas E . Platelet and mean platelet volume kinetics in adult patients with sepsis. Platelets. 2012; 26(4):331-5. DOI: 10.3109/09537104.2012.701027. View

Kulah B, Kulacoglu I, Oruc M, Duzgun A, Moran M, Ozmen M . Presentation and outcome of incarcerated external hernias in adults. Am J Surg. 2001; 181(2):101-4. DOI: 10.1016/s0002-9610(00)00563-8. View

Kulah B, Duzgun A, Moran M, Kulacoglu I, Ozmen M, Coskun F . Emergency hernia repairs in elderly patients. Am J Surg. 2002; 182(5):455-9. DOI: 10.1016/s0002-9610(01)00765-6. View

Kurt N, Oncel M, Ozkan Z, Bingul S . Risk and outcome of bowel resection in patients with incarcerated groin hernias: retrospective study. World J Surg. 2003; 27(6):741-3. DOI: 10.1007/s00268-003-6826-x. View

10.

Alvarez J, Baldonedo R, Bear I, Solis J, Alvarez P, Jorge J . Incarcerated groin hernias in adults: presentation and outcome. Hernia. 2003; 8(2):121-6. DOI: 10.1007/s10029-003-0186-1. View

11.

Greisenegger S, Endler G, Hsieh K, Tentschert S, Mannhalter C, Lalouschek W . Is elevated mean platelet volume associated with a worse outcome in patients with acute ischemic cerebrovascular events?. Stroke. 2004; 35(7):1688-91. DOI: 10.1161/01.STR.0000130512.81212.a2. View

12.

Taniguchi T, Takagi D, Takeyama N, Kitazawa Y, Tanaka T . Platelet size and function in septic rats: changes in the adenylate pool. J Surg Res. 1990; 49(5):400-7. DOI: 10.1016/0022-4804(90)90187-7. View

13.

Moller L, Kristensen T . Plasma fibrinogen and ischemic heart disease risk factors. Arterioscler Thromb. 1991; 11(2):344-50. DOI: 10.1161/01.atv.11.2.344. View

14.

Heys S, Brittenden J . Strangulated femoral hernia: the persisting clinical trap. Postgrad Med J. 1991; 67(783):57-9. PMC: 2398924. DOI: 10.1136/pgmj.67.783.57. View

15.

Khandekar M, Khurana A, Deshmukh S, Kakrani A, Katdare A, Inamdar A . Platelet volume indices in patients with coronary artery disease and acute myocardial infarction: an Indian scenario. J Clin Pathol. 2006; 59(2):146-9. PMC: 1860313. DOI: 10.1136/jcp.2004.025387. View

16.

ODwyer P, Norrie J, Alani A, Walker A, Duffy F, Horgan P . Observation or operation for patients with an asymptomatic inguinal hernia: a randomized clinical trial. Ann Surg. 2006; 244(2):167-73. PMC: 1602168. DOI: 10.1097/01.sla.0000217637.69699.ef. View

17.

Becchi C, Al Malyan M, Fabbri L, Marsili M, Boddi V, Boncinelli S . Mean platelet volume trend in sepsis: is it a useful parameter?. Minerva Anestesiol. 2006; 72(9):749-56. View

18.

van der Lelie J, Von dem Borne A . Increased mean platelet volume in septicaemia. J Clin Pathol. 1983; 36(6):693-6. PMC: 498352. DOI: 10.1136/jcp.36.6.693. View