Psychopathological Symptoms of Patients with Heroin Addiction Entering Opioid Agonist or Therapeutic Community Treatment

Overview

Journal Ann Gen Psychiatry

Publisher Biomed Central

Specialty Psychiatry

Date 2014 Dec 2

PMID 25435897

Citations 11

Authors

Pier Paolo Pani

Emanuela Trogu

Federica Vigna-Taglianti

Federica Mathis

Roberto Diecidue

Ursula Kirchmayer

Laura Amato

Marina Davoli

Joli Ghibaudi

Antonella Camposeragna

Alessio Saponaro

Fabrizio Faggiano

Angelo Giovanni Icro Maremmani

Icro Maremmani

Affiliations

Soon will be listed here.

Abstract

Background: The relationship between substance use disorders and psychiatric pathology is still an open question. The main aim of the present study was to verify whether the five psychopathological dimensions identified through the SCL-90 tool in a previous study carried out on patients with heroin addiction entering an outpatient opioid agonist treatment (OAT) were also observable in those entering a residential treatment community (TC). Further aims were to look at differences in the psychopathological profiles of patients entering a TC versus an OAT treatment and at the correlation between gender and the observed psychopathology.

Methods: A confirmatory factor analysis was performed on the results of SCL-90 filled by 1,195 patients with heroin dependence entering TC treatment. It replicates the extraction method previously used on 1,055 OAT patients with heroin addiction by using a principal component factor analysis (PCA). The association between the kind of treatment received (TC or OAT), gender, and the psychopathological dimensions was assessed through logistic regression and general linear model (GLM) analysis.

Results: The PCA carried out on the SCL-90 results of patients entering a TC yielded a five-factor solution, confirming the same dimensions observed in patients entering an OAT: 'worthlessness and being trapped', 'somatization', 'sensitivity-psychoticism', 'panic anxiety', and 'violence-suicide'. The logistic regression analysis showed a statistically significant association between 'somatization' and 'violence-suicide' severity score and OAT. GLM analysis showed that psychopathological factorial scores for 'worthlessness-being trapped', 'somatic symptoms', and 'panic anxiety' dimensions were more severe in OAT vs TC male patients and in TC vs OAT female ones. 'Violence suicide' followed the same severity pattern for males, but did not differ in TC vs OAT females, while 'sensitivity-psychoticism' did not differ in OAT vs TC patients. The five dimensions did not differ in OAT males vs females.

Conclusions: Our research appears to confirm the existence of a specific aggregation of psychological/psychiatric features within the category of individuals with heroin addiction. It also shows a correlation between the dominant psychopathological subgroup and the assignment to TC versus OAT. Further research is needed to clarify the differences between the five psychopathological subgroups and their determinants.

Citing Articles

Characteristics of Stress Sensitivity in Heroin Use Disorder Patients during Their Opioid Agonist Treatment.

Della Rocca F, Maremmani A, Bacciardi S, Pacini M, Lamanna F, Tripodi B Int J Environ Res Public Health. 2023; 20(5).

PMID: 36901575 PMC: 10002439. DOI: 10.3390/ijerph20054566.

Delineating the Psychic Structure of Substance Use and Addictions, from Neurobiology to Clinical Implications: Ten Years Later.

Pani P, Maremmani A, Pacini M, Trogu E, Gessa G, Ruiz P J Clin Med. 2020; 9(6).

PMID: 32570932 PMC: 7356689. DOI: 10.3390/jcm9061913.

Co-Occurring Psychiatric and Substance Use Disorders: Clinical Survey Among a Rural Cohort of Italian Patients.

Milano G, Vergani H, Cattedra S, Carrozzino R, Mattioli F, Robbiano L Neuropsychiatr Dis Treat. 2020; 15:3453-3459.

PMID: 31908460 PMC: 6927221. DOI: 10.2147/NDT.S222567.

Psychopathology of addiction: Can the SCL90-based five-dimensional structure differentiate Heroin Use Disorder from a non-substance-related addictive disorder such as Gambling Disorder?.

Maremmani A, Gazzarrini D, Fiorin A, Cingano V, Bellio G, Perugi G Ann Gen Psychiatry. 2018; 17:3.

PMID: 29371875 PMC: 5769351. DOI: 10.1186/s12991-018-0173-7.

A Self-Report Measure to Detect Neurocognitive Impairment among Incarcerated People Living with HIV in Malaysian Context: An Exploratory Factor Analysis.

Shrestha R, Weikum D, Copenhaver M, Altice F Int J Ment Health Addict. 2017; 15(4):812-825.

PMID: 29051714 PMC: 5642920. DOI: 10.1007/s11469-017-9752-0.

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