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Community Acquired Panton-Valentine Leukocidin (PVL) Positive Methicilin Resistant Staphylococcal Aureus Cerebral Abscess in an 11-month Old Boy: a Case Study

Overview
Journal BMC Res Notes
Publisher Biomed Central
Specialties Biology
General Medicine
Date 2014 Dec 2
PMID 25435087
Authors
Wilbroad Mutale
Keya M Sahay
John Hartley
Dominic Thompson
Didi Ratnasinghe
Lee Hudson
Eleanor Hulse
Greg Fellows
Affiliations
Soon will be listed here.
Abstract

Background: Brain abscess are uncommon childhood infection. Brain abscess caused by Panton-Valentine Leukocidin positive Community acquired Methicillin Resistant Staphylococcal aureus have never been reported in the United Kingdom.

Case Presentation: We report a case of a previously well 11-month old boy of Indian origin who developed a parietal lobe abscess from PVL positive CA-MRSA.

Conclusion: This case is one of the few described cases of brain abscess caused by PVL CA-MRSA in children. The unusual (insidious) presentation, the absence of a clear staphylococcal focus and the unexpected finding of a CA-MRSA in this patient highlight the challenges of managing such cases in clinical settings and the potential future risk to public health.

Citing Articles

Severe Panton-Valentine-Leukocidin-Positive Infections in Pediatric Age: A Case Report and a Literature Review.

Garbo V, Venuti L, Boncori G, Albano C, Condemi A, Natoli G Antibiotics (Basel). 2025; 13(12.

PMID: 39766583 PMC: 11672633. DOI: 10.3390/antibiotics13121192.

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