Cohort Profile Update: the TRacking Adolescents' Individual Lives Survey (TRAILS)

Overview

Journal Int J Epidemiol

Specialty Public Health

Date 2014 Nov 29

PMID 25431468

Citations 75

Authors

Albertine J Oldehinkel

Judith Gm Rosmalen

Jan K Buitelaar

Hans W Hoek

Johan Ormel

Dennis Raven

Sijmen A Reijneveld

Rene Veenstra

Frank C Verhulst

Wilma Am Vollebergh

Catharina A Hartman

Affiliations

Soon will be listed here.

Abstract

TRAILS consists of a population cohort (N=2230) and a clinical cohort (N=543), both of which were followed from about age 11 years onwards. To date, the population cohort has been assessed five times over a period of 11 years, with retention rates ranging between 80% and 96%. The clinical cohort has been assessed four times over a period of 8 years, with retention rates ranging between 77% and 85%. Since the IJE published a cohort profile on the TRAILS in 2008, the participants have matured from adolescents into young adults. The focus shifted from parents and school to entry into the labour market and family formation, including offspring. Furthermore, psychiatric diagnostic interviews were administered, the database was linked to a Psychiatric Case Registry, and the availability of genome-wide SNP variations opened the door to genome-wide association studies regarding a wide range of (endo)phenotypes. With some delay, TRAILS data are available to researchers outside the TRAILS consortium without costs; access can be obtained by submitting a publication proposal (see www.trails.nl).

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