Ultrahigh-speed Swept-source OCT Angiography in Exudative AMD

Overview

Journal Ophthalmic Surg Lasers Imaging Retina

Specialties General Surgery
Ophthalmology
Radiology

Date 2014 Nov 26

PMID 25423628

Citations 100

Authors

Eric Moult

WooJhon Choi

Nadia K Waheed

Mehreen Adhi

ByungKun Lee

Chen D Lu

Vijaysekhar Jayaraman

Benjamin Potsaid

Philip J Rosenfeld

Jay S Duker

James G Fujimoto

Affiliations

Soon will be listed here.

Abstract

Background And Objective: To investigate the potential of ultrahigh-speed swept-source optical coherence tomography angiography (OCTA) to visualize retinal and choroidal vascular changes in patients with exudative age-related macular degeneration (AMD).

Patients And Methods: Observational, prospective cross-sectional study. An ultrahigh-speed swept-source prototype was used to perform OCTA of the retinal and choriocapillaris microvasculature in 63 eyes of 32 healthy controls and 19 eyes of 15 patients with exudative AMD.

Main Outcome Measure: qualitative comparison of the retinal and choriocapillaris microvasculature in the two groups.

Results: Choroidal neovascularization (CNV) was clearly visualized in 16 of the 19 eyes with exudative AMD, located above regions of severe choriocapillaris alteration. In 14 of these eyes, the CNV lesions were surrounded by regions of choriocapillaris alteration.

Conclusion: OCTA may offer noninvasive monitoring of the retinal and choriocapillaris microvasculature in patients with CNV, which may assist in diagnosis and monitoring.

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