Lipid-based Patterning of the Immunological Synapse

Overview

Journal Biochem Soc Trans

Specialty Biochemistry

Date 2014 Nov 18

PMID 25399561

Citations 8

Authors

Morgan Huse

Affiliations

Soon will be listed here.

Abstract

The immunological synapse controls T-lymphocyte function by polarizing effector responses towards the antigen-presenting cell. In this review, I discuss the molecular pathways required for synapse assembly, focusing on the central roles played by lipid second-messenger signalling.

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