Biosensing by Luminogens with Aggregation-induced Emission Characteristics

Overview

Journal Chem Soc Rev

Specialty Chemistry

Date 2014 Nov 7

PMID 25374162

Citations 148

Authors

Ryan T K Kwok

Chris W T Leung

Jacky W Y Lam

Ben Zhong Tang

Affiliations

Soon will be listed here.

Abstract

Fluorescent biosensors are powerful analytical tools for studying biological events in living systems. Luminescent materials with aggregation-induced emission (AIE) attributes have attracted much research interest and have been identified as a novel class of luminogens to develop fluorescent turn-on biosensors with superior sensitivity. In this Tutorial Review, we present an overview of the AIE phenomenon and its mechanism. We summarize the structural design and working principle of AIE biosensors developed recently. Typical examples of AIE biosensors are presented.

Citing Articles

Photoresponsive Helical Foldamers: Conformational Control Through Double Helix Formation and Light-Induced Protonation.

Hardoin L, Kdouh R, Aidibi Y, Azar S, Siegler B, Allain M Chemistry. 2025; 31(11):e202403771.

PMID: 39749723 PMC: 11840663. DOI: 10.1002/chem.202403771.

CO-promoted photocatalytic aryl migration from nitrogen to carbon for switchable transformation of N-arylpropiolamides.

Liu G, Ma D, Zhang J, Yang F, Gao Y, Su W Nat Commun. 2024; 15(1):10153.

PMID: 39578418 PMC: 11584665. DOI: 10.1038/s41467-024-54239-5.

Excited State Dynamics of Geometrical Evolution of α-Substituted Dibenzoylmethanatoboron Difluoride Complex with Aggregation-Induced Emission Property.

Fujimoto Y, Mochiduki Y, Sotome H, Shimada R, Okajima H, Toda Y J Am Chem Soc. 2024; 146(47):32529-32538.

PMID: 39550714 PMC: 11613315. DOI: 10.1021/jacs.4c10277.

Unveiling Invisible Extracellular Vesicles: Cutting-Edge Technologies for Their in Vivo Visualization.

Gangadaran P, Khan F, Rajendran R, Onkar A, Goenka A, Ahn B Wiley Interdiscip Rev Nanomed Nanobiotechnol. 2024; 16(5):e2009.

PMID: 39439198 PMC: 11670046. DOI: 10.1002/wnan.2009.

Aggregation-Induced Emission Luminogen: Role in Biopsy for Precision Medicine.

Duo Y, Han L, Yang Y, Wang Z, Wang L, Chen J Chem Rev. 2024; 124(20):11242-11347.

PMID: 39380213 PMC: 11503637. DOI: 10.1021/acs.chemrev.4c00244.