» Articles » PMID: 25368636

Heat-sensitive Moxibustion Attenuates the Inflammation After Focal Cerebral Ischemia/ Reperfusion Injury

Overview
Date 2014 Nov 5
PMID 25368636
Citations 4
Authors
Affiliations
Soon will be listed here.
Abstract

Heat-sensitive moxibustion has neuroprotective effects against focal cerebral ischemia/reperfusion injury, however its mechanism of action remains unclear. In this study, rat models of focal cerebral ischemia/reperfusion injury were treated with suspended moxibustion at acupoint Dazhui (DU14) for 35 minutes. Results showed that suspended moxibustion decreased infarct volume, reduced cortical myeloperoxidase activity, and suppressed serum levels of proinflammatory cytokines in rats with focal cerebral ischemia/reperfusion injury. Our experimental findings indicated that heat-sensitive moxibustion can attenuate inflammation and promote repair after focal cerebral ischemia/reperfusion injury.

Citing Articles

Sevoflurane Post-treatment Upregulated miR-203 Expression to Attenuate Cerebral Ischemia-Reperfusion-Induced Neuroinflammation by Targeting MyD88.

Zhong H, Chen H, Gu C Inflammation. 2020; 43(2):651-663.

PMID: 31897915 DOI: 10.1007/s10753-019-01147-2.


Efficacy and safety of moxibustion in patients with chronic prostatitis/chronic pelvic pain syndrome: A systematic review protocol.

Cao Q, Zhou X, Chen J, Zhong Y, Zhang H, Ao Q Medicine (Baltimore). 2019; 98(20):e15678.

PMID: 31096505 PMC: 6531205. DOI: 10.1097/MD.0000000000015678.


Effect of Different Dosages of ST36 Indirect Moxibustion on the Skin Temperature of the Lower Legs and Feet.

Kuge H, Mori H, Morisawa T, Hanyu K, Miyazaki J, Watanabe M Medicines (Basel). 2018; 5(2).

PMID: 29914073 PMC: 6023346. DOI: 10.3390/medicines5020057.


P2X₇ receptor of rat dorsal root ganglia is involved in the effect of moxibustion on visceral hyperalgesia.

Liu S, Shi Q, Zhu Q, Zou T, Li G, Huang A Purinergic Signal. 2014; 11(2):161-9.

PMID: 25527178 PMC: 4425718. DOI: 10.1007/s11302-014-9439-y.

References
1.
Elango C, Niranjali Devaraj S . Immunomodulatory effect of Hawthorn extract in an experimental stroke model. J Neuroinflammation. 2011; 7:97. PMC: 3022819. DOI: 10.1186/1742-2094-7-97. View

2.
Bederson J, Pitts L, Germano S, Nishimura M, Davis R, Bartkowski H . Evaluation of 2,3,5-triphenyltetrazolium chloride as a stain for detection and quantification of experimental cerebral infarction in rats. Stroke. 1986; 17(6):1304-8. DOI: 10.1161/01.str.17.6.1304. View

3.
Longa E, Weinstein P, Carlson S, Cummins R . Reversible middle cerebral artery occlusion without craniectomy in rats. Stroke. 1989; 20(1):84-91. DOI: 10.1161/01.str.20.1.84. View

4.
Kao T, Ou Y, Liao S, Chen W, Wang C, Chen S . Opioids modulate post-ischemic progression in a rat model of stroke. Neurochem Int. 2008; 52(6):1256-65. DOI: 10.1016/j.neuint.2008.01.007. View

5.
Rao P, Zhou L, Mao M, Bai Y, Wen T, Tang Y . [A randomized controlled trial of acupuncture treatment of acute ischemic stroke]. Zhongguo Zhen Jiu. 2006; 26(10):694-6. View