Hybrid ZnO Nanorod-polymer Brush Hierarchically Nanostructured Substrate for Sensitive Antibody Microarrays

Overview

Journal Adv Mater

Date 2014 Nov 5

PMID 25366876

Citations 15

Authors

Weihua Hu

Yingshuai Liu

Tao Chen

Yang Liu

Chang Ming Li

Affiliations

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Abstract

A hierarchically nanostructured organic-inorganic hybrid substrate comprising randomly oriented ZnO nanorods on glass slide with coaxially tethered dense polymer brush, POEGMA-co-GMA is reported for highly sensitive antibody microassay, achieving excellent detection specificity, and superior detection limit of as low as 100 fg mL(-1) for biomarkers in human serum within a 1 h assay time.

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