Acupoint Catgut Embedding Therapy with Moxibustion Reduces the Risk of Diabetes in Obese Women

Overview

Journal J Res Med Sci

Specialty General Medicine

Date 2014 Nov 4

PMID 25364359

Citations 13

Authors

Jessica M Garcia-Vivas

Carlos Galaviz-Hernandez

Flavia Becerril-Chavez

Francisco Lozano-Rodriguez

Absalom Zamorano-Carrillo

Cesar Lopez-Camarillo

Laurence A Marchat

Affiliations

Soon will be listed here.

Abstract

Background: Obesity is a major health problem worldwide for which conventional therapy efficacy is limited. Traditional Chinese medicine, particularly body acupoint stimulation, provides an alternative, effective, and safe therapy for this medical challenge. The present study was designed to compare the effects of distinct methods to stimulate the same set of acupoints, on anthropometric and biochemical parameters in obese women.

Materials And Methods: Ninety-nine obese women were randomly assigned to six groups of treatment: Acupuncture with moxibustion, long needle acupuncture with moxibustion, electroacupuncture (EA), EA with moxibustion, embedded catgut with moxibustion (CGM) and sham acupuncture as control. Obesity-related parameters, including body weight, body mass index (BMI), waist and hip circumferences, waist/hip ratio, biochemical parameters (triglycerides, cholesterol, glucose, insulin) and homeostasis model of assessment - insulin resistance (HOMA-IR) index, were determined before and after each treatment.

Results: Body weight and BMI were significantly reduced in response to all treatments. Interestingly, acupoint catgut embedding therapy combined with moxibustion was the only treatment that produced a significant reduction in body weight (3.1 ± 0.2 kg, P < 0.001), BMI (1.3 ± 0.1 kg/m(2), P < 0.001), insulin (3.5 ± 0.8 mcU/ml, P < 0.1) and HOMA-IR (1.4 ± 0.2 units, P < 0.01) in comparison with sham group. Furthermore, this treatment was able to bring back obese women to a state of insulin sensitivity, indicating that acupoint catgut embedding therapy combined with moxibustion could be useful as a complementary therapy to reduce the risk of diabetes associated to obesity in women.

Conclusion: Overall, our results confirmed the effectiveness of acupoints stimulation to assist in the control of body weight in women. They also highlighted the more favorable effects of embedded catgut-moxibustion combination that may be due to the extended and consistent stimulation of acupoints.

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References

Yu M, Xiao X, Tang C, Liu Z, Hou Y, Gao J . [Effect of different intensities of electroacupuncture on expression of monocyte chemoattractant protein-1 and TNF-alpha in adipose tissue in obesity rats]. Zhen Ci Yan Jiu. 2011; 36(2):79-84. View

Cabioglu M, Ergene N, Surucu H, Celik H, Findik D . Serum IgG, IgA, IgM, and IgE levels after electroacupuncture and diet therapy in obese women. Am J Chin Med. 2008; 35(6):955-65. DOI: 10.1142/S0192415X07005429. View

Darbandi M, Darbandi S, Mobarhan M, Owji A, Zhao B, Iraji K . Effects of auricular acupressure combined with low-calorie diet on the leptin hormone in obese and overweight Iranian individuals. Acupunct Med. 2012; 30(3):208-13. DOI: 10.1136/acupmed-2011-010121. View

Gucel F, Bahar B, Demirtas C, Mit S, Cevik C . Influence of acupuncture on leptin, ghrelin, insulin and cholecystokinin in obese women: a randomised, sham-controlled preliminary trial. Acupunct Med. 2012; 30(3):203-7. DOI: 10.1136/acupmed-2012-010127. View

Cabioglu M, Gundogan N, Ergene N . The efficacy of electroacupuncture therapy for weight loss changes plasma lipoprotein A, apolipoprotein A and apolipoprotein B levels in obese women. Am J Chin Med. 2008; 36(6):1029-39. DOI: 10.1142/S0192415X08006430. View

Shi Y, Zhang L, Zhao C, He C . [Comparison of therapeutic effects of acupuncture-cupping plus acupoint catgut embedding and electroacupuncture on simple obesity of stomach and intestine excess-heat type]. Zhongguo Zhen Jiu. 2006; 26(8):547-50. View

Qu H, Li Q, Rentfro A, Fisher-Hoch S, McCormick J . The definition of insulin resistance using HOMA-IR for Americans of Mexican descent using machine learning. PLoS One. 2011; 6(6):e21041. PMC: 3114864. DOI: 10.1371/journal.pone.0021041. View

Takakura N, Yajima H . A double-blind placebo needle for acupuncture research. BMC Complement Altern Med. 2007; 7:31. PMC: 2176062. DOI: 10.1186/1472-6882-7-31. View

Popkin B, Adair L, Ng S . Global nutrition transition and the pandemic of obesity in developing countries. Nutr Rev. 2012; 70(1):3-21. PMC: 3257829. DOI: 10.1111/j.1753-4887.2011.00456.x. View

10.

Tang C, Dai D, Zhao G, Zhu W, Mei L . [Clinical observation on electroacupuncture combined with catgut implantation at acupoints for treatment of simple obesity of heart and spleen deficiency type]. Zhongguo Zhen Jiu. 2009; 29(9):703-7. View

11.

Ren J, Kelley R . Cardiac health in women with metabolic syndrome: clinical aspects and pathophysiology. Obesity (Silver Spring). 2009; 17(6):1114-23. DOI: 10.1038/oby.2009.8. View

12.

Cabioglu M, Ergene N . Changes in levels of serum insulin, C-Peptide and glucose after electroacupuncture and diet therapy in obese women. Am J Chin Med. 2006; 34(3):367-76. DOI: 10.1142/S0192415X06003904. View

13.

Abdi H, Zhao B, Darbandi M, Ghayour-Mobarhan M, Tavallaie S, Rahsepar A . The effects of body acupuncture on obesity: anthropometric parameters, lipid profile, and inflammatory and immunologic markers. ScientificWorldJournal. 2012; 2012:603539. PMC: 3353309. DOI: 10.1100/2012/603539. View

14.

Balkau B, Charles M, Drivsholm T, Borch-Johnsen K, Wareham N, Yudkin J . Frequency of the WHO metabolic syndrome in European cohorts, and an alternative definition of an insulin resistance syndrome. Diabetes Metab. 2002; 28(5):364-76. View

15.

Gao L, Kong X, Shi X . [Effects of electroacupuncture and acupoint catgut-embedding on mRNA expression of lipid metabolism gene PPAR-gamma and related lipase of rats with simple obesity]. Zhongguo Zhen Jiu. 2011; 31(6):535-8. View

16.

Cabioglu M, Ergene N . Electroacupuncture therapy for weight loss reduces serum total cholesterol, triglycerides, and LDL cholesterol levels in obese women. Am J Chin Med. 2005; 33(4):525-33. DOI: 10.1142/S0192415X05003132. View

17.

Chen F, Wu S, Zhang Y . [Effect of acupoint catgut embedding on TNF-alpha and insulin resistance in simple obesity patients]. Zhen Ci Yan Jiu. 2007; 32(1):49-52. View

18.

Sullivan P, Ghushchyan V, Wyatt H, Wu E, Hill J . Impact of cardiometabolic risk factor clusters on health-related quality of life in the U.S. Obesity (Silver Spring). 2007; 15(2):511-21. DOI: 10.1038/oby.2007.580. View

19.

Yan R, Liu X, Bai J, Hou B, Yu J, Gu J . Clinical efficacy of simple obesity treated by catgut implantation at acupoints. Chin J Integr Med. 2012; 21(8):594-600. DOI: 10.1007/s11655-012-1215-7. View

20.

Flegal K, Carroll M, Ogden C, Curtin L . Prevalence and trends in obesity among US adults, 1999-2008. JAMA. 2010; 303(3):235-41. DOI: 10.1001/jama.2009.2014. View