MicroRNA-1 in Cardiac Diseases and Cancers

Overview

Journal Korean J Physiol Pharmacol

Specialty Pharmacology

Date 2014 Oct 30

PMID 25352753

Citations 22

Authors

Jianzhe Li

Xiaomin Dong

Zhongping Wang

Jianhua Wu

Affiliations

Soon will be listed here.

Abstract

MicroRNAs (miRs) are endogenous ≈22-nt non-coding RNAs that participate in the regulation of gene expression at post-transcriptional level. MiR-1 is one of the muscle-specific miRs, aberrant expression of miR-1 plays important roles in many physiological and pathological processes. In this review, we focus on the recent studies about miR-1 in cardiac diseases and cancers. The findings indicate that miR-1 may be a novel, important biomarker, and a potential therapeutic target in cardiac diseases and cancers.

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