Arterial Wall Function is Associated with Cognitive Performance Primarily in Elderly with Type 2 Diabetes

Overview

Journal J Alzheimers Dis

Publisher Sage Publications

Specialties Geriatrics
Neurology

Date 2014 Oct 30

PMID 25352451

Authors

Ramit Ravona-Springer

Salo Haratz

David Tanne

James Schmeidler

Shai Efrati

Clive Rosendorff

Michal Schnaider Beeri

Jeremy M Silverman

Affiliations

Soon will be listed here.

Abstract

Regression analyses compared 41 type 2 diabetes (T2D) and 131 non-T2D cognitively normal elderly males on the associations of arterial wall function measures [large artery elasticity index (LAEI), small artery elasticity index (SAEI), systemic vascular resistance (SVR), and total vascular impedance (TVI)] with cognitive performance (memory, language, and executive functions), controlling for socio-demographic and cardiovascular factors. Higher LAEI and lower TVI were significantly associated with better executive functions performance in T2D but not in non-T2D subjects. Lower TVI was more associated with better language performance in T2D. Results suggest that arterial wall function is associated with cognition in T2D.

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