Management of Gynecological Cancers During Pregnancy

Overview

Journal Curr Oncol Rep

Publisher Current Science

Specialty Oncology

Date 2014 Oct 26

PMID 25344340

Citations 14

Authors

Sileny N Han

Magali Verheecke

Tineke Vandenbroucke

Mina Mhallem Gziri

Kristel Van Calsteren

Frederic Amant

Affiliations

Soon will be listed here.

Abstract

The diagnosis of a gynecological malignancy during pregnancy is rare but not uncommon. Cancer treatment during pregnancy is possible, but both maternal and fetal interests need to be respected. Different treatment plans may be justifiable and multidisciplinary treatment is advised. Clinical trials are virtually impossible, and current evidence is mainly based on small case series and expert opinion. Individualization of treatment is necessary and based on tumor type, stage, and gestational age at time of diagnosis. Termination of pregnancy is not necessary in most cases. Surgery and chemotherapy (second trimester and onwards) are possible types of treatment during pregnancy. Radiotherapy of the pelvic area is not compatible with an ongoing pregnancy. This article discusses the current recommendations for the management of gynecological malignancies (cervical, ovarian, and vulvar cancers) during pregnancy.

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