Deciphering Thymic Development

Overview

Journal Front Immunol

Specialty Allergy & Immunology

Date 2014 Oct 24

PMID 25339947

Citations 2

Authors

Harald von Boehmer

Affiliations

Soon will be listed here.

Citing Articles

Treatment With FoxP3+ Antigen-Experienced T Regulatory Cells Arrests Progressive Retinal Damage in a Spontaneous Model of Uveitis.

Liu Y, Molzer C, Makinen K, Kamoi K, Corbett C, Klaska I Front Immunol. 2020; 11:2071.

PMID: 33013877 PMC: 7498671. DOI: 10.3389/fimmu.2020.02071.

Spontaneous partial loss of the OT-I transgene.

Pritchard G, Cross E, Strobel M, Jameson S, Kedl R, Hogquist K Nat Immunol. 2016; 17(5):471.

PMID: 27092794 PMC: 5073790. DOI: 10.1038/ni.3411.

References

Trowsdale J, Hanson I, Mockridge I, Beck S, Townsend A, Kelly A . Sequences encoded in the class II region of the MHC related to the 'ABC' superfamily of transporters. Nature. 1990; 348(6303):741-4. DOI: 10.1038/348741a0. View

von Boehmer H, Hengartner H, Nabholz M, Lernhardt W, SCHREIER M, Haas W . Fine specificity of a continuously growing killer cell clone specific for H-Y antigen. Eur J Immunol. 1979; 9(8):592-7. DOI: 10.1002/eji.1830090804. View

Monaco J, Cho S, Attaya M . Transport protein genes in the murine MHC: possible implications for antigen processing. Science. 1990; 250(4988):1723-6. DOI: 10.1126/science.2270487. View

Kreslavsky T, Kim H, Koralov S, Ghitza D, Buch T, Cantor H . Negative selection, not receptor editing, is a physiological response of autoreactive thymocytes. J Exp Med. 2013; 210(10):1911-8. PMC: 3782038. DOI: 10.1084/jem.20130876. View

Kappler J, Roehm N, Marrack P . T cell tolerance by clonal elimination in the thymus. Cell. 1987; 49(2):273-80. DOI: 10.1016/0092-8674(87)90568-x. View

Teh H, Kisielow P, Scott B, Kishi H, Uematsu Y, Bluthmann H . Thymic major histocompatibility complex antigens and the alpha beta T-cell receptor determine the CD4/CD8 phenotype of T cells. Nature. 1988; 335(6187):229-33. DOI: 10.1038/335229a0. View

Townsend A, Ohlen C, Bastin J, Ljunggren H, Foster L, Karre K . Association of class I major histocompatibility heavy and light chains induced by viral peptides. Nature. 1989; 340(6233):443-8. DOI: 10.1038/340443a0. View

Kisielow P, Teh H, Bluthmann H, von Boehmer H . Positive selection of antigen-specific T cells in thymus by restricting MHC molecules. Nature. 1988; 335(6192):730-3. DOI: 10.1038/335730a0. View

Rosenthal A, Shevach E . Function of macrophages in antigen recognition by guinea pig T lymphocytes. I. Requirement for histocompatible macrophages and lymphocytes. J Exp Med. 1973; 138(5):1194-212. PMC: 2139433. DOI: 10.1084/jem.138.5.1194. View

10.

Deverson E, Gow I, Coadwell W, Monaco J, Butcher G, Howard J . MHC class II region encoding proteins related to the multidrug resistance family of transmembrane transporters. Nature. 1990; 348(6303):738-41. DOI: 10.1038/348738a0. View

11.

Dembic Z, Haas W, Weiss S, McCubrey J, Kiefer H, von Boehmer H . Transfer of specificity by murine alpha and beta T-cell receptor genes. Nature. 1986; 320(6059):232-8. DOI: 10.1038/320232a0. View

12.

Egawa T, Littman D . ThPOK acts late in specification of the helper T cell lineage and suppresses Runx-mediated commitment to the cytotoxic T cell lineage. Nat Immunol. 2008; 9(10):1131-9. PMC: 2666788. DOI: 10.1038/ni.1652. View

13.

Kisielow P, Bluthmann H, Staerz U, Steinmetz M, von Boehmer H . Tolerance in T-cell-receptor transgenic mice involves deletion of nonmature CD4+8+ thymocytes. Nature. 1988; 333(6175):742-6. DOI: 10.1038/333742a0. View

14.

Murata S, Sasaki K, Kishimoto T, Niwa S, Hayashi H, Takahama Y . Regulation of CD8+ T cell development by thymus-specific proteasomes. Science. 2007; 316(5829):1349-53. DOI: 10.1126/science.1141915. View

15.

Katz D, Hamaoka T, Benacerraf B . Cell interactions between histoincompatible T and B lymphocytes. II. Failure of physiologic cooperative interactions between T and B lymphocytes from allogeneic donor strains in humoral response to hapten-protein conjugates. J Exp Med. 1973; 137(6):1405-18. PMC: 2139346. DOI: 10.1084/jem.137.6.1405. View

16.

Zinkernagel R, Doherty P . MHC-restricted cytotoxic T cells: studies on the biological role of polymorphic major transplantation antigens determining T-cell restriction-specificity, function, and responsiveness. Adv Immunol. 1979; 27:51-177. DOI: 10.1016/s0065-2776(08)60262-x. View

17.

Scott B, Bluthmann H, Teh H, von Boehmer H . The generation of mature T cells requires interaction of the alpha beta T-cell receptor with major histocompatibility antigens. Nature. 1989; 338(6216):591-3. DOI: 10.1038/338591a0. View

18.

He X, Park K, Kappes D . The role of ThPOK in control of CD4/CD8 lineage commitment. Annu Rev Immunol. 2010; 28:295-320. DOI: 10.1146/annurev.immunol.25.022106.141715. View

19.

Spies T, Bresnahan M, Bahram S, Arnold D, Blanck G, Mellins E . A gene in the human major histocompatibility complex class II region controlling the class I antigen presentation pathway. Nature. 1990; 348(6303):744-7. DOI: 10.1038/348744a0. View