The Comparative Study of Yaz and Ovocept-ld on Patients with Simple Ovarian Cysts Referring to Iran-Isfahan Shariati Hospital

Overview

Journal Adv Biomed Res

Specialty Biomedical Engineering

Date 2014 Oct 23

PMID 25337535

Citations 1

Authors

Soheyla Riahinejad

Azam Foroughi Pour

Leila Dehghani

Saadat Hajizadeh

Affiliations

Soon will be listed here.

Abstract

Background: Functional ovarian cysts include follicular, corpus luteum, and theca lutein cysts are the most common adnexal masses (about 50%) in women of reproductive age. Treatment with the combined monophasic oral contraceptives reduces functional ovarian cysts. Yaz (drospirenone/ethinyl estradiol) is a low-dose combined oral contraceptive pill containing 20 μg ethinyl estradiol and 3 mg drospirenone. In addition to contraceptive effects, Yaz has anti-mineralocorticoid and anti-adrenergic effects. Ovocept- low-dose LD is also a low-dose combined oral contraceptive drug containing 30 μg ethinyl estradiol and 3 mg norgestrol. Ovocept-LD has some side-effects such as weight gain, spotting, breast tenderness, nausea, and headache.

Materials And Methods: Being a clinical study, the present research was carried out on 42 patients with the simple ovarian cysts from 2010 to 2012. 84 Patients were assigned to A and B groups. Group A received Yaz once a day for a period of 28 days and group B received Ovocept-LD once a day for a period of 21 days. After treating by Yaz and Ovocept-LD, Cysts were evaluated by ultrasound. Results were analyzed by the SPSS software. A P < 0.05 was considered the significance threshold.

Results: Obtained results indicated that both Yaz and Ovocept-LD had an effect on the simple ovarian cysts. Statistical tests, however, has shown that the effect of Yaz has been significantly more than that of Ovocept-LD.

Conclusion: Given the faster and better recovery effect, and the lesser side effects of Yaz as compared to Ovocept-LD, it is recommended to use Yaz for the simple ovarian cysts.

Citing Articles

Parity and risk of ovarian cysts: Cross-sectional evidence from the Dongfeng-Tongji cohort study.

Mandiwa C, Shen L, Tian Y, Song L, Xu G, Yang S J Huazhong Univ Sci Technolog Med Sci. 2016; 36(5):767-771.

PMID: 27752898 DOI: 10.1007/s11596-016-1659-7.

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