Effect of Acute Sleep Deprivation on Heart Rate Recovery in Healthy Young Adults

Overview

Journal Sleep Breath

Publisher Springer

Date 2014 Oct 17

PMID 25319876

Citations 15

Authors

Altug Cincin

Ibrahim Sari

Mustafa Oguz

Sena Sert

Mehmet Bozbay

Halil Atas

Beste Ozben

Kursat Tigen

Yelda Basaran

Affiliations

Soon will be listed here.

Abstract

Background: Sleep deprivation (SD) is known to be associated with increased incidence of adverse cardiovascular events, but underlying pathophysiological mechanism has not been clearly demonstrated. Autonomic nervous system plays an important role in the regulation of cardiovascular function, and impairment in this system is associated with increased cardiovascular mortality. The aim of the current study was to investigate the effect of acute SD on autonomic regulation of cardiac function by determining heart rate recovery (HRR).

Methods: Twenty-one healthy security officers and nine nurses (mean age 33.25 ± 8.18) were evaluated. Treadmill exercise test was applied once after a night with regular sleep and once after a night shift in hospital. The HRR was calculated as the reduction in heart rate from peak exercise to the 30th second (HRR30), 1st minute (HRR1), 2nd minute (HRR2), 3rd minute (HRR3), and 5th minute (HRR5). The change in blood pressure (BP) measurements was also determined.

Results: Exercise capacity of individuals with SD was significantly lower (10.96 ± 1.01 vs. 11.71 ± 1.30 metabolic equivalent task (MET)s; p = 0.002), and peak systolic BP was significantly higher (173.8 ± 16.3 vs. 166.2 ± 9.9; p = 0.019). There was a signicant difference in HRR30 (12.74 ± 6.19 vs. 17.66 ± 5.46; p = 0.003) and HRR1 (31 ± 6.49 vs. 36.10 ± 7.78; p = 0.004). The ratio of these indices to peak HR was also significantly lower with SD (HRR%30 8.04 ± 4.26 vs. 10.19 ± 3.21; p = 0.025 and HRR%1: 18.66 ± 4.43 vs. 20.98 ± 4.72; p = 0.013). The difference in other indices of HRR was not significant.

Conclusion: Our findings suggest that SD blunts cardiovascular autonomic response, and consequences of this relation might be more pronounced in subjects who are exposed to sleeplessness regularly or in subjects with baseline cardiovascular disease.

Citing Articles

Joint association of sedentary time and physical activity with abnormal heart rate recovery in young and middle-aged adults.

Liu Z, Zheng P, Fang Y, Huang J, Huang J, Chen L BMC Public Health. 2024; 24(1):1787.

PMID: 38965484 PMC: 11225313. DOI: 10.1186/s12889-024-19298-9.

Ckip-1 3'UTR alleviates prolonged sleep deprivation induced cardiac dysfunction by activating CaMKK2/AMPK/cTNI pathway.

Dong B, Xue R, Li J, Ling S, Xing W, Liu Z Mol Biomed. 2024; 5(1):23.

PMID: 38871861 PMC: 11176284. DOI: 10.1186/s43556-024-00186-y.

Sleep Deprivation and Heart Rate Variability in Healthy Volunteers: Effects of REM and SWS Sleep Deprivation.

Xu Y, Qu B, Liu F, Gong Z, Zhang Y, Xu D Comput Math Methods Med. 2023; 2023:7121295.

PMID: 37469834 PMC: 10353901. DOI: 10.1155/2023/7121295.

Acute sleep deprivation: impairment of biventricular function assesed by speckle tracking echocardiography in healthy subjects.

Bingol G, Avci Demir F, Ozmen E, Unlu S, Ozden O, Boyuk F Sleep Breath. 2023; 27(6):2241-2247.

PMID: 37099093 DOI: 10.1007/s11325-023-02837-w.

Long-Term Sleep Deprivation-Induced Myocardial Remodeling and Mitochondrial Dysfunction in Mice Were Attenuated by Lipoic Acid and -Acetylcysteine.

Song F, Lin J, Zhang H, Guo Y, Mao Y, Liu Z Pharmaceuticals (Basel). 2023; 16(1).

PMID: 36678548 PMC: 9866495. DOI: 10.3390/ph16010051.

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