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Comparative Analysis of Mg-dependent and Mg-independent HCO3(-) ATPases

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Journal J Membr Biol
Date 2014 Oct 17
PMID 25319124
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Abstract

The comparative analysis between two enzymes, Mg-dependent and Mg-independent HCO3(-) ATPases, were studied in synaptosomal and microsomal membrane fractions of albino rat brain, using the method of kinetic analysis of the multi-sited enzyme systems. Therefore, it can be inferred that Mg-dependent HCO3(-) ATPase belongs to the group of "P-type" transporting ATPases. Mg-independent HCO3(-) ATPase with its kinetic properties may be attributed to the group of "Ecto" ATPases.

References
1.
Dzneladze S, Tsakadze L, Leladze M, Kometiani Z . Cl anion-dependent Mg-ATPase. J Membr Biol. 2012; 245(3):151-6. PMC: 3319893. DOI: 10.1007/s00232-012-9423-9. View

2.
Drakulich D, Spellmon C, Hexum T . Effect of the ecto-ATPase inhibitor, ARL 67156, on the bovine chromaffin cell response to ATP. Eur J Pharmacol. 2004; 485(1-3):137-40. DOI: 10.1016/j.ejphar.2003.11.056. View

3.
KOMETIANI Z, Tsakadze L, Jariashvili TYa . Functional significance of the effects of neurotransmitters on the Na+,K+-ATPase system. J Neurochem. 1984; 42(5):1246-50. DOI: 10.1111/j.1471-4159.1984.tb02779.x. View

4.
Gassner D, Komnick H . Inhibition of a Cl-/HCO3(-)ATPase in the avian salt gland by furosemide and ethacrynic acid. Cell Biol Int Rep. 1981; 5(3):239-46. DOI: 10.1016/0309-1651(81)90222-8. View

5.
Levesque S, Lavoie E, Lecka J, Bigonnesse F, Sevigny J . Specificity of the ecto-ATPase inhibitor ARL 67156 on human and mouse ectonucleotidases. Br J Pharmacol. 2007; 152(1):141-50. PMC: 1978278. DOI: 10.1038/sj.bjp.0707361. View