» Articles » PMID: 25309742

Filial Caregiving is Associated with Greater Neuroendocrine Dysfunction: Evidence from the 2005 National Survey of Midlife in the U.S

Overview
Journal SAGE Open Med
Publisher Sage Publications
Specialty General Medicine
Date 2014 Oct 14
PMID 25309742
Citations 7
Authors
Affiliations
Soon will be listed here.
Abstract

Objectives: This study examined associations between providing caregiving for a biological or adoptive parent and clinically-assessed biological risk factors (allostatic load [AL] and its three subscales - inflammatory dysfunction, metabolic dysfunction, neuroendocrine dysfunction), as well as moderation of these associations by gender.

Method: Regression models were estimated using telephone and self-report data from 962 men and women who participated in the National Survey of Midlife in the U.S. (MIDUS) 2005.

Results: Filial caregivers demonstrated higher levels of neuroendocrine dysfunction. No gender difference in biological risks was found.

Discussion: Filial caregiving is the most prevalent form of family caregiving and results indicating the presence of greater neuroendocrine dysfunction among filial caregivers in contrast to noncaregivers suggest an important public health concern. Future research needs to continue to examine different relationship types of caregivers and include a range of biological risk measurement to further the understanding of how family caregiving is linked to biological health risks.

Citing Articles

Multiple forms of discrimination and inflammation in Black Americans: Are there differences by sex?.

Byrd D, Allen J Soc Sci Med. 2023; 321:115785.

PMID: 36801746 PMC: 10072201. DOI: 10.1016/j.socscimed.2023.115785.


Assessing the role of socioeconomic status and discrimination exposure for racial disparities in inflammation.

Cuevas A, Goler E, Guetta C, Krueger R Brain Behav Immun. 2022; 102:333-337.

PMID: 35307502 PMC: 9073909. DOI: 10.1016/j.bbi.2022.03.005.


The transition to family caregiving and its effect on biomarkers of inflammation.

Roth D, Haley W, Sheehan O, Huang J, Rhodes J, Durda P Proc Natl Acad Sci U S A. 2020; 117(28):16258-16263.

PMID: 32581123 PMC: 7368336. DOI: 10.1073/pnas.2000792117.


Transitions to family caregiving: enrolling incident caregivers and matched non-caregiving controls from a population-based study.

Roth D, Haley W, Rhodes J, Sheehan O, Huang J, Blinka M Aging Clin Exp Res. 2019; 32(9):1829-1838.

PMID: 31630377 PMC: 8577452. DOI: 10.1007/s40520-019-01370-9.


Biomedical health profiles of unpaid family carers in an urban population in South Australia.

Stacey A, Gill T, Price K, Taylor A PLoS One. 2019; 14(3):e0208434.

PMID: 30921333 PMC: 6438668. DOI: 10.1371/journal.pone.0208434.


References
1.
Cacioppo J, Burleson M, Poehlmann K, Malarkey W, Kiecolt-Glaser J, Berntson G . Autonomic and neuroendocrine responses to mild psychological stressors: effects of chronic stress on older women. Ann Behav Med. 2000; 22(2):140-8. DOI: 10.1007/BF02895778. View

2.
Pinquart M, Sorensen S . Associations of stressors and uplifts of caregiving with caregiver burden and depressive mood: a meta-analysis. J Gerontol B Psychol Sci Soc Sci. 2003; 58(2):P112-28. DOI: 10.1093/geronb/58.2.p112. View

3.
Damjanovic A, Yang Y, Glaser R, Kiecolt-Glaser J, Nguyen H, Laskowski B . Accelerated telomere erosion is associated with a declining immune function of caregivers of Alzheimer's disease patients. J Immunol. 2007; 179(6):4249-54. PMC: 2262924. DOI: 10.4049/jimmunol.179.6.4249. View

4.
Asch S, Kerr E, Keesey J, Adams J, Setodji C, Malik S . Who is at greatest risk for receiving poor-quality health care?. N Engl J Med. 2006; 354(11):1147-56. DOI: 10.1056/NEJMsa044464. View

5.
Vedhara K, Cox N, Wilcock G, Perks P, Hunt M, Anderson S . Chronic stress in elderly carers of dementia patients and antibody response to influenza vaccination. Lancet. 1999; 353(9153):627-31. DOI: 10.1016/S0140-6736(98)06098-X. View