Perimetry, Retinal Nerve Fiber Layer Thickness and Papilledema Grade After Cerebrospinal Fluid Shunting in Patients with Idiopathic Intracranial Hypertension

Overview

Journal J Neuroophthalmol

Specialties Neurology
Ophthalmology

Date 2014 Oct 9

PMID 25295682

Citations 5

Authors

Jennifer L Rizzo

Khoa V Lam

Michael Wall

Machelle D Wilson

John L Keltner

Affiliations

Soon will be listed here.

Abstract

Background: To investigate the effect of cerebrospinal fluid (CSF) shunting on quantitative perimetry and papilledema in patients with uncontrolled idiopathic intracranial hypertension (IIH).

Methods: We retrospectively reviewed all cases of IIH with CSF shunting at our institution between 2004 and 2011. Perimetry was performed before and after surgery in 15 patients, and the mean deviation (MD) was compared before and after surgery to assess the effect of the intervention.

Results: Fourteen of the IIH patients were female and 1 was male. The average age was 34 years. CSF shunting resulted in significant improvement in the perimetric results with an increase in the MD of 5.63 ± 1.19 dB (P < 0.0001). Additionally, average retinal nerve fiber layer (RNFL) thickness measurement by optical coherence tomography decreased by 87.27 ± 16.65 μm (P < 0.0001), and Frisen papilledema grade decreased by 2.19 ± 0.71 (P < 0.0001).

Conclusions: Our results suggest that CSF shunting results in improvement in perimetry, RNFL swelling, and papilledema grade in patients with IIH.

Citing Articles

Optic Nerve Head and Retinal Changes in Idiopathic Intracranial Hypertension: Correlation with Short-Term Cerebrospinal Fluid Pressure Monitoring.

Toro M, Castellino N, Russo A, Scollo D, Avitabile T, Rejdak R J Clin Med. 2024; 13(2).

PMID: 38256695 PMC: 10816298. DOI: 10.3390/jcm13020562.

Resolution of Papilledema Following Ventriculoperitoneal Shunt or Endoscopic Third Ventriculostomy for Obstructive Hydrocephalus: A Pilot Study.

Das S, Montemurro N, Ashfaq M, Ghosh D, Sarker A, Khan A Medicina (Kaunas). 2022; 58(2).

PMID: 35208604 PMC: 8879089. DOI: 10.3390/medicina58020281.

A systematic review of surgical treatments of idiopathic intracranial hypertension (IIH).

Kalyvas A, Neromyliotis E, Koutsarnakis C, Komaitis S, Drosos E, Skandalakis G Neurosurg Rev. 2020; 44(2):773-792.

PMID: 32335853 DOI: 10.1007/s10143-020-01288-1.

Update on Idiopathic Intracranial Hypertension.

Kanagalingam S, Subramanian P Curr Treat Options Neurol. 2018; 20(7):24.

PMID: 29808423 DOI: 10.1007/s11940-018-0512-7.

Idiopathic intracranial hypertension occurred after spinal surgery: report of two rare cases and systematic review of the literature.

Xu Z, Li H, Chen G, Li F, Qian S, Chen Q Eur Spine J. 2016; 26(Suppl 1):9-16.

PMID: 27188182 DOI: 10.1007/s00586-016-4578-1.

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