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Long-term Periodontal Tissue Outcome in Regenerated Infrabony and Furcation Defects: a Systematic Review

Overview
Specialty Dentistry
Date 2014 Oct 9
PMID 25293498
Citations 2
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Abstract

Objectives: This study aimed to systematically evaluate the long-term results of periodontal tissues in regenerated infrabony and furcation defects.

Material And Methods: A search of the Medline database was performed (1960 to 2012), complimented by an additional hand search. For inclusion in the review, clinical trials had to include the long-term evaluation of infrabony and furcation defects submitted to periodontal regeneration for up to 3 years of follow-up. Changes in clinical attachment level (CAL) from pre-surgery, at the first post-surgical, and final evaluations were used to analyze the effects of regenerative treatments over time.

Results: A total of 866 articles were found using the descriptors employed. Of these, 216 papers were selected for abstract reading by two evaluators. One hundred and eighty-nine were excluded for not fulfilling the eligibility criteria. Twenty-seven papers were selected for the analysis of the full texts, and 13 were excluded. Two studies were included after a manual search. Finally, 16 papers were selected for the present review.

Conclusions: Regenerative techniques for the treatment of infrabony and furcation defects resulted in improved CAL during long-term follow-up periods, even when attachment losses occurred during this period. This improvement should be carefully evaluated with regard to its clinical relevance for dental longevity.

Clinical Relevance: The improvement in clinical attachment level achieved by regenerative techniques with biomaterials demonstrated satisfactory results over the long-term. However, regenerative techniques still present different success rates with regard to gain in clinical attachment level.

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References
1.
Gottlow J, Nyman S, Lindhe J, Karring T, Wennstrom J . New attachment formation in the human periodontium by guided tissue regeneration. Case reports. J Clin Periodontol. 1986; 13(6):604-16. DOI: 10.1111/j.1600-051x.1986.tb00854.x. View

2.
Heijl L, Heden G, Svardstrom G, Ostgren A . Enamel matrix derivative (EMDOGAIN) in the treatment of intrabony periodontal defects. J Clin Periodontol. 1997; 24(9 Pt 2):705-14. DOI: 10.1111/j.1600-051x.1997.tb00253.x. View

3.
van der Pauw M, van den Bos T, Everts V, Beertsen W . Enamel matrix-derived protein stimulates attachment of periodontal ligament fibroblasts and enhances alkaline phosphatase activity and transforming growth factor beta1 release of periodontal ligament and gingival fibroblasts. J Periodontol. 2000; 71(1):31-43. DOI: 10.1902/jop.2000.71.1.31. View

4.
Orsini M, Orsini G, Benlloch D, Aranda J, Sanz M . Long-term clinical results on the use of bone-replacement grafts in the treatment of intrabony periodontal defects. Comparison of the use of autogenous bone graft plus calcium sulfate to autogenous bone graft covered with a bioabsorbable membrane. J Periodontol. 2008; 79(9):1630-7. DOI: 10.1902/jop.2008.070282. View

5.
Pretzl B, Kim T, Steinbrenner H, Dorfer C, Himmer K, Eickholz P . Guided tissue regeneration with bioabsorbable barriers III 10-year results in infrabony defects. J Clin Periodontol. 2009; 36(4):349-56. DOI: 10.1111/j.1600-051X.2009.01378.x. View