Randomized Controlled Trial of Interpersonal Psychotherapy Versus Enhanced Treatment As Usual for Women with Co-occurring Depression and Pelvic Pain

Overview

Journal J Psychosom Res

Specialty Psychiatry

Date 2014 Oct 5

PMID 25280823

Citations 4

Authors

Ellen L Poleshuck

Stephanie A Gamble

Kelly Bellenger

Naiji Lu

Xin Tu

Silvia Sorensen

Donna E Giles

Nancy L Talbot

Affiliations

Soon will be listed here.

Abstract

Objective: Our study assessed the effectiveness of Interpersonal Psychotherapy (IPT) tailored for biomedical patients with depression and pain. IPT was compared to enhanced treatment as usual (E-TAU) among women with co-occurring depression and chronic pain presenting for care at a women's health or family medicine practice. We hypothesized that women presenting to urban medical practices with depression and chronic pain would benefit from IPT tailored to address their needs to a greater degree than from E-TAU.

Methods: We conducted a randomized controlled psychotherapy trial of 61 women from 2 urban medical practices who met criteria for major depressive disorder and chronic pelvic pain. Participants were assigned to receive either 8 sessions of IPT or a facilitated psychotherapy referral to a community mental health center, and assessed for depression, social interactions, and pain at 0-, 12-, 24-, and 36-weeks, with score on the Hamilton Rating Scale for Depression as the primary outcome. Both intent-to-treat (ITT) and causal modeling analyses correcting for treatment attendance were conducted.

Results: ITT analyses were not significant. In causal modeling analyses, participants assigned to IPT showed significantly more improvement for depression and social interactions, but not for pain.

Conclusion: IPT may be a viable option as part of a comprehensive treatment program for women in medical practices with depression and chronic pain.

Clinical Trials Registration: ClinicalTrials.gov, NCT00895999.

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