A Quantitative Assessment of the Association Between 1425G/A Polymorphism in PRKCH and Risk of Stroke

Overview

Journal Neuromolecular Med

Specialty Biochemistry

Date 2014 Oct 3

PMID 25272991

Citations 2

Authors

Lingli Sun

Zhizhong Zhang

Minmin Ma

Gelin Xu

Xinfeng Liu

Affiliations

Soon will be listed here.

Abstract

Ga/gg: OR 1.35, 95% CI 1.12-1.62, P = 0.002; A vs. G: OR 1.29, 95% CI 1.21-1.39, P < 0.001). In the subgroup analysis, significantly increased risks were also observed for ischemic stroke, larger sample size (>1,000) and population-based studies. The result of our meta-analysis indicated that the 1425G/A SNP in PRKCH may contribute to susceptibility of stroke, especially for ischemic stroke.

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