Embolization of Symptomatic Renal Angiomyolipoma with a Mixture of Lipiodol and PVA, a Mid-term Result

Overview

Journal Chin J Cancer Res

Specialty Oncology

Date 2014 Sep 19

PMID 25232211

Citations 8

Authors

Qiang Huang

Ren-You Zhai

Affiliations

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Abstract

Objective: To evaluate the clinical effect of renal artery embolization with a mixture of lipiodol and polyvinyl alcohol (PVA) particles on symptomatic renal angiomyolipoma and to present the mid-term results from our single-center site.

Methods: We performed a retrospective review of the seven patients who underwent embolization with a mixture of lipiodol and PVA particles to treat symptomatic renal angiomyolipoma in our center between February 2011 and December 2013. Medical records and follow-up results were reviewed and analyzed.

Results: Seven patients underwent eight episodes of embolization using a mixture of lipiodol and PVA particles to treat symptomatic renal angiomyolipoma. One patient required a subsequent embolization of the right kidney 9 months after the initial embolization of the left kidney. No nephrectomy was required in any of these cases during follow-up. None had recurrence of tumor bleeding or rupture during follow-up. Decreased tumor size was achieved in six patients (85.7%) during the mid-term follow-up.

Conclusions: Embolization with a mixture of lipiodol and PVA particles is an effective and safe treatment for symptomatic renal angiomyolipoma. Based on the durable mid-term results of the present study, a mixture of lipiodol and PVA particles is recommended for embolization.

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References

Seyam R, Bissada N, Kattan S, Mokhtar A, Aslam M, Fahmy W . Changing trends in presentation, diagnosis and management of renal angiomyolipoma: comparison of sporadic and tuberous sclerosis complex-associated forms. Urology. 2008; 72(5):1077-82. DOI: 10.1016/j.urology.2008.07.049. View

Idee J, Guiu B . Use of Lipiodol as a drug-delivery system for transcatheter arterial chemoembolization of hepatocellular carcinoma: a review. Crit Rev Oncol Hematol. 2013; 88(3):530-49. DOI: 10.1016/j.critrevonc.2013.07.003. View

Lenton J, Kessel D, Watkinson A . Embolization of renal angiomyolipoma: immediate complications and long-term outcomes. Clin Radiol. 2008; 63(8):864-70. DOI: 10.1016/j.crad.2008.02.005. View

Halpenny D, Snow A, McNeill G, Torreggiani W . The radiological diagnosis and treatment of renal angiomyolipoma-current status. Clin Radiol. 2010; 65(2):99-108. DOI: 10.1016/j.crad.2009.09.014. View

Chan C, Yu S, Yip S, Lee P . The efficacy, safety and durability of selective renal arterial embolization in treating symptomatic and asymptomatic renal angiomyolipoma. Urology. 2010; 77(3):642-8. DOI: 10.1016/j.urology.2010.08.040. View

Lee S, Hsu H, Chen Y, Huang C, Wong Y, Wang L . Embolization of renal angiomyolipomas: short-term and long-term outcomes, complications, and tumor shrinkage. Cardiovasc Intervent Radiol. 2009; 32(6):1171-8. DOI: 10.1007/s00270-009-9637-0. View

Urciuoli P, DOrazi V, Livadoti G, Foresi E, Panunzi A, Anichini S . Treatment of renal angiomyolipoma: surgery versus angioembolization. G Chir. 2013; 34(11-12):326-31. PMC: 3926473. View

Mues A, Palacios J, Haramis G, Casazza C, Badani K, Gupta M . Contemporary experience in the management of angiomyolipoma. J Endourol. 2010; 24(11):1883-6. DOI: 10.1089/end.2010.0223. View

Katada Y, Umehara I, Ohki T, Kishino M, Shibuya H . Bilateral renal angiomyolipoma in a patient with tuberous sclerosis treated with resection of one kidney and transarterial embolization of other kidney using CT during selective arteriography: a case report. Cases J. 2009; 2:6351. PMC: 2740105. DOI: 10.4076/1757-1626-2-6351. View

10.

Ramon J, Rimon U, Garniek A, Golan G, BenSaid P, Kitrey N . Renal angiomyolipoma: long-term results following selective arterial embolization. Eur Urol. 2008; 55(5):1155-61. DOI: 10.1016/j.eururo.2008.04.025. View

11.

Chick C, Tan B, Cheng C, Taneja M, Lo R, Tan Y . Long-term follow-up of the treatment of renal angiomyolipomas after selective arterial embolization with alcohol. BJU Int. 2009; 105(3):390-4. DOI: 10.1111/j.1464-410X.2009.08813.x. View

12.

Abrams J, Yee D, Clark T . Transradial embolization of a bleeding renal angiomyolipoma. Vasc Endovascular Surg. 2011; 45(5):470-3. DOI: 10.1177/1538574411408352. View

13.

Baba Y, Hayashi S, Ikeda S, Jinguji M, Nakajo M, Nakajo M . Evaluation of split renal function before and after renal arterial embolization for angiomyolipoma using absolute ethanol. Cardiovasc Intervent Radiol. 2013; 37(5):1220-5. DOI: 10.1007/s00270-013-0780-2. View

14.

Rimon U, Duvdevani M, Garniek A, Golan G, BenSaid P, Ramon J . Ethanol and polyvinyl alcohol mixture for transcatheter embolization of renal angiomyolipoma. AJR Am J Roentgenol. 2006; 187(3):762-8. DOI: 10.2214/AJR.05.0629. View