Trunkloads of Viruses

Overview

Journal J Virol

Publisher American Society for Microbiology

Date 2014 Sep 19

PMID 25231304

Citations 9

Authors

Philip E Pellett

Affiliations

Soon will be listed here.

Abstract

Elephant populations are under intense pressure internationally from habitat destruction and poaching for ivory and meat. They also face pressure from infectious agents, including elephant endotheliotropic herpesvirus 1 (EEHV1), which kills ~20% of Asian elephants (Elephas maximus) born in zoos and causes disease in the wild. EEHV1 is one of at least six distinct EEHV in a phylogenetic lineage that appears to represent an ancient but newly recognized subfamily (the Deltaherpesvirinae) in the family Herpesviridae.

Citing Articles

Patterns of Genital Tract (Musghv-1) Reactivation Are Linked to Stressors in European Badgers ().

Tsai M, Francois S, Newman C, Macdonald D, Buesching C Biomolecules. 2021; 11(5).

PMID: 34064759 PMC: 8151406. DOI: 10.3390/biom11050716.

Effects of (MusGHV-1) Reactivation in European Badger () Genital Tracts on Reproductive Fitness.

Tsai M, Fogarty U, Byrne A, OKeeffe J, Newman C, Macdonald D Pathogens. 2020; 9(9).

PMID: 32962280 PMC: 7559395. DOI: 10.3390/pathogens9090769.

Extended genotypic evaluation and comparison of twenty-two cases of lethal EEHV1 hemorrhagic disease in wild and captive Asian elephants in India.

Zachariah A, Sajesh P, Santhosh S, Bathrachalam C, Megha M, Pandiyan J PLoS One. 2018; 13(8):e0202438.

PMID: 30133540 PMC: 6105008. DOI: 10.1371/journal.pone.0202438.

Identification of shedders of elephant endotheliotropic herpesviruses among Asian elephants (Elephas maximus) in Switzerland.

Ackermann M, Hatt J, Schetle N, Steinmetz H PLoS One. 2017; 12(5):e0176891.

PMID: 28467495 PMC: 5415103. DOI: 10.1371/journal.pone.0176891.

Herpesviral capture of immunomodulatory host genes.

Schonrich G, Abdelaziz M, Raftery M Virus Genes. 2017; 53(6):762-773.

PMID: 28451945 DOI: 10.1007/s11262-017-1460-0.

References

Rose T, Schultz E, Henikoff J, Pietrokovski S, McCALLUM C, Henikoff S . Consensus-degenerate hybrid oligonucleotide primers for amplification of distantly related sequences. Nucleic Acids Res. 1998; 26(7):1628-35. PMC: 147464. DOI: 10.1093/nar/26.7.1628. View

VanDevanter D, Warrener P, Bennett L, Schultz E, Coulter S, Garber R . Detection and analysis of diverse herpesviral species by consensus primer PCR. J Clin Microbiol. 1996; 34(7):1666-71. PMC: 229091. DOI: 10.1128/JCM.34.7.1666-1671.1996. View

Davison A, Eberle R, Ehlers B, Hayward G, McGeoch D, Minson A . The order Herpesvirales. Arch Virol. 2008; 154(1):171-7. PMC: 3552636. DOI: 10.1007/s00705-008-0278-4. View

Roizman B, Carmichael L, Deinhardt F, Nahmias A, Plowright W, Rapp F . Herpesviridae. Definition, provisional nomenclature, and taxonomy. The Herpesvirus Study Group, the International Committee on Taxonomy of Viruses. Intervirology. 1981; 16(4):201-17. DOI: 10.1159/000149269. View

Hayward G . Conservation: clarifying the risk from herpesvirus to captive Asian elephants. Vet Rec. 2012; 170(8):202-3. PMC: 3587150. DOI: 10.1136/vr.e1212. View

Ehlers B, Burkhardt S, Goltz M, BERGMANN V, Ochs A, Weiler H . Genetic and ultrastructural characterization of a European isolate of the fatal endotheliotropic elephant herpesvirus. J Gen Virol. 2001; 82(Pt 3):475-482. DOI: 10.1099/0022-1317-82-3-475. View

Wellehan J, Johnson A, Childress A, Harr K, Isaza R . Six novel gammaherpesviruses of Afrotheria provide insight into the early divergence of the Gammaherpesvirinae. Vet Microbiol. 2007; 127(3-4):249-57. DOI: 10.1016/j.vetmic.2007.08.024. View

Richman L, Montali R, Garber R, Kennedy M, Lehnhardt J, Hildebrandt T . Novel endotheliotropic herpesviruses fatal for Asian and African elephants. Science. 1999; 283(5405):1171-6. DOI: 10.1126/science.283.5405.1171. View

Richman L, Zong J, Latimer E, Lock J, Fleischer R, Heaggans S . Elephant endotheliotropic herpesviruses EEHV1A, EEHV1B, and EEHV2 from cases of hemorrhagic disease are highly diverged from other mammalian herpesviruses and may form a new subfamily. J Virol. 2014; 88(23):13523-46. PMC: 4248956. DOI: 10.1128/JVI.01673-14. View

10.

Zong J, Latimer E, Long S, Richman L, Heaggans S, Hayward G . Comparative genome analysis of four elephant endotheliotropic herpesviruses, EEHV3, EEHV4, EEHV5, and EEHV6, from cases of hemorrhagic disease or viremia. J Virol. 2014; 88(23):13547-69. PMC: 4248975. DOI: 10.1128/JVI.01675-14. View

11.

Dominguez G, Dambaugh T, Stamey F, Dewhurst S, Inoue N, Pellett P . Human herpesvirus 6B genome sequence: coding content and comparison with human herpesvirus 6A. J Virol. 1999; 73(10):8040-52. PMC: 112820. DOI: 10.1128/JVI.73.10.8040-8052.1999. View

12.

Latimer E, Zong J, Heaggans S, Richman L, Hayward G . Detection and evaluation of novel herpesviruses in routine and pathological samples from Asian and African elephants: identification of two new probosciviruses (EEHV5 and EEHV6) and two new gammaherpesviruses (EGHV3B and EGHV5). Vet Microbiol. 2010; 147(1-2):28-41. PMC: 2976818. DOI: 10.1016/j.vetmic.2010.05.042. View

13.

Wilkie G, Davison A, Watson M, Kerr K, Sanderson S, Bouts T . Complete genome sequences of elephant endotheliotropic herpesviruses 1A and 1B determined directly from fatal cases. J Virol. 2013; 87(12):6700-12. PMC: 3676107. DOI: 10.1128/JVI.00655-13. View

14.

Ling P, Reid J, Qin X, Muzny D, Gibbs R, Petrosino J . Complete Genome Sequence of Elephant Endotheliotropic Herpesvirus 1A. Genome Announc. 2013; 1(2):e0010613. PMC: 3624679. DOI: 10.1128/genomeA.00106-13. View