Traumatic Brain Injury: A Case-based Review
Overview
Authors
Affiliations
Background: Traumatic brain injuries are common and costly to hospital systems. Most of the guidelines on management of traumatic brain injuries are taken from the Brain Trauma Foundation Guidelines. This is a review of the current literature discussing the evolving practice of traumatic brain injury.
Data Sources: A literature search using multiple databases was performed for articles published through September 2012 with concentration on meta-analyses, systematic reviews, and randomized controlled trials.
Results: The focus of care should be to minimize secondary brain injury by surgically decompressing certain hematomas, maintain systolic blood pressure above 90 mmHg, oxygen saturations above 93%, euthermia, intracranial pressures below 20 mmHg, and cerebral perfusion pressure between 60-80 mmHg.
Conclusion: Much is still unknown about the management of traumatic brain injury. The current practice guidelines have not yet been sufficiently validated, however equipoise is a major issue when conducting randomized control trials among patients with traumatic brain injury.
Salah M, Saatchi R, Lecky F, Burke D Healthc Technol Lett. 2020; 7(5):119-124.
PMID: 33282321 PMC: 7704143. DOI: 10.1049/htl.2019.0029.
Optical coherence tomography microscopy in experimental traumatic brain injury.
Osiac E, Mitran S, Manea C, Cojocaru A, Rosu G, Osiac M Microsc Res Tech. 2020; 84(3):422-431.
PMID: 33009699 PMC: 7891427. DOI: 10.1002/jemt.23599.
Kord Z, Alimohammadi N, Jafari Mianaei S, Riazi A, Zarasvand B Pediatric Health Med Ther. 2020; 11:269-275.
PMID: 32848495 PMC: 7429226. DOI: 10.2147/PHMT.S260720.
Chi F, Lang T, Sun S, Tang X, Xu S, Zheng H World J Emerg Med. 2014; 5(3):203-8.
PMID: 25225585 PMC: 4163813. DOI: 10.5847/wjem.j.issn.1920-8642.2014.03.008.
Expression of tissue factor in rabbit pulmonary artery in an acute pulmonary embolism model.
Zhang J, Chen Y, Zhou Y, Guo Q, Wang X World J Emerg Med. 2014; 5(2):144-7.
PMID: 25215165 PMC: 4129874. DOI: 10.5847/wjem.j.issn.1920-8642.2014.02.012.