Host-microbe Interactions and Spatial Variation of Cancer in the Gut

Overview

Journal Nat Rev Cancer

Specialty Oncology

Date 2014 Sep 10

PMID 25202783

Citations 8

Authors

Fergus Shanahan

Paul W OToole

Affiliations

Soon will be listed here.

Abstract

The small intestine has a greater cell mass than the colon, it is longer and with greater surface area and has a faster rate of epithelial turnover. At first, this might suggest that the small bowel epithelium could be at greater risk of the cumulative genetic errors that predispose to cancer. However, the incidence of cancer of the small bowel is more than tenfold lower than that of colorectal cancer.

Citing Articles

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KMP01D Demonstrates Beneficial Anti-inflammatory Effects on Immune Cells: An Preclinical Study of Patients With Colorectal Cancer.

Gasser M, Lissner R, Nawalaniec K, Hsiao L, Waaga-Gasser A Front Immunol. 2020; 11:684.

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An enrichment model using regular health examination data for early detection of colorectal cancer.

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CCMP: software-as-a-service approach for fully-automated microbiome profiling.

Park S, Nanda S, Faraci G, Park Y, Lee H J Biomed Inform X. 2019; 2.

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Gut bacteria are required for the benefits of black raspberries in mice.

Pan P, Oshima K, Huang Y, Yearsley M, Zhang J, Arnold M J Berry Res. 2019; 8(4):239-249.

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