Associations of Adherence to the New Nordic Diet with Risk of Preeclampsia and Preterm Delivery in the Norwegian Mother and Child Cohort Study (MoBa)

Overview

Journal Eur J Epidemiol

Specialty Public Health

Date 2014 Sep 7

PMID 25193741

Citations 34

Authors

Elisabet Rudjord Hillesund

Nina C Overby

Stephanie M Engel

Kari Klungsoyr

Quaker E Harmon

Margaretha Haugen

Elling Bere

Affiliations

Soon will be listed here.

Abstract

Preeclampsia and preterm delivery are serious complications of pregnancy and leading causes of perinatal mortality and morbidity worldwide. Dietary factors might be associated with these adverse outcomes. We investigated whether adherence to the New Nordic Diet (NND) was associated with preeclampsia and preterm delivery risks in the Norwegian Mother and Child Cohort Study (MoBa). Participants were recruited from all over Norway during the period 1999-2008. A previously constructed diet score assessing meal frequency, and the consumption of Nordic fruits, root vegetables, cabbages, potatoes, oatmeal porridge, whole grains, wild fish, game, berries, milk and water, was used to assess NND adherence. Associations between NND adherence and the outcomes were estimated in adjusted multivariate logistic regression models. Odds ratios (ORs) and 95 % confidence intervals (CIs) were calculated. A total of 72,072 women was included in the study. High versus low NND adherence was associated with lower risk of total preeclampsia (OR 0.86; 95 % CI 0.78-0.95) and early preeclampsia (OR 0.71; 95 % CI 0.52-0.96). High compared with low NND adherence was associated with a lower risk of spontaneous preterm delivery among nulliparous women (OR 0.77; 95 % CI 0.66-0.89), whereas multiparous women with high NND adherence had a marginally significant higher risk of preterm delivery (OR 1.24; 95 % CI 1.00-1.53). High NND adherence was associated with a lower relative risk of preeclampsia and of spontaneous preterm delivery among nulliparous women; however, among multiparous women there was a higher relative risk of preterm delivery.

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References

Brennan L, Morton J, Davidge S . Vascular dysfunction in preeclampsia. Microcirculation. 2013; 21(1):4-14. DOI: 10.1111/micc.12079. View

Haugen M, Meltzer H, Brantsaeter A, Mikkelsen T, Osterdal M, Alexander J . Mediterranean-type diet and risk of preterm birth among women in the Norwegian Mother and Child Cohort Study (MoBa): a prospective cohort study. Acta Obstet Gynecol Scand. 2008; 87(3):319-24. DOI: 10.1080/00016340801899123. View

Mudd L, Holzman C, Catov J, Senagore P, Evans R . Maternal lipids at mid-pregnancy and the risk of preterm delivery. Acta Obstet Gynecol Scand. 2012; 91(6):726-35. PMC: 4563824. DOI: 10.1111/j.1600-0412.2012.01391.x. View

Kyro C, Skeie G, Loft S, Overvad K, Christensen J, Tjonneland A . Adherence to a healthy Nordic food index is associated with a lower incidence of colorectal cancer in women: the Diet, Cancer and Health cohort study. Br J Nutr. 2012; 109(5):920-7. DOI: 10.1017/S0007114512002085. View

Thomsen L, Klungsoyr K, Roten L, Tappert C, Araya E, Baerheim G . Validity of the diagnosis of pre-eclampsia in the Medical Birth Registry of Norway. Acta Obstet Gynecol Scand. 2013; 92(8):943-50. DOI: 10.1111/aogs.12159. View

Ozkan H, Cetinkaya M, Koksal N . Increased incidence of bronchopulmonary dysplasia in preterm infants exposed to preeclampsia. J Matern Fetal Neonatal Med. 2012; 25(12):2681-5. DOI: 10.3109/14767058.2012.708371. View

Crozier S, Robinson S, Godfrey K, Cooper C, Inskip H . Women's dietary patterns change little from before to during pregnancy. J Nutr. 2009; 139(10):1956-63. PMC: 3113465. DOI: 10.3945/jn.109.109579. View

Savitz D, Harmon Q, Siega-Riz A, Herring A, Dole N, Thorp Jr J . Behavioral influences on preterm birth: integrated analysis of the pregnancy, infection, and nutrition study. Matern Child Health J. 2011; 16(6):1151-63. PMC: 3605739. DOI: 10.1007/s10995-011-0895-5. View

Brader L, Uusitupa M, Dragsted L, Hermansen K . Effects of an isocaloric healthy Nordic diet on ambulatory blood pressure in metabolic syndrome: a randomized SYSDIET sub-study. Eur J Clin Nutr. 2013; 68(1):57-63. DOI: 10.1038/ejcn.2013.192. View

10.

Qiu C, Coughlin K, Frederick I, Sorensen T, Williams M . Dietary fiber intake in early pregnancy and risk of subsequent preeclampsia. Am J Hypertens. 2008; 21(8):903-9. DOI: 10.1038/ajh.2008.209. View

11.

Sibai B, Dekker G, Kupferminc M . Pre-eclampsia. Lancet. 2005; 365(9461):785-99. DOI: 10.1016/S0140-6736(05)17987-2. View

12.

Roswall N, Olsen A, Boll K, Christensen J, Halkjaer J, Sorensen T . Consumption of predefined 'Nordic' dietary items in ten European countries - an investigation in the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort. Public Health Nutr. 2014; 17(12):2650-9. PMC: 10282376. DOI: 10.1017/S1368980014000159. View

13.

Englund-Ogge L, Brantsaeter A, Sengpiel V, Haugen M, Birgisdottir B, Myhre R . Maternal dietary patterns and preterm delivery: results from large prospective cohort study. BMJ. 2014; 348:g1446. PMC: 3942565. DOI: 10.1136/bmj.g1446. View

14.

Magnus P, Irgens L, Haug K, Nystad W, Skjaerven R, Stoltenberg C . Cohort profile: the Norwegian Mother and Child Cohort Study (MoBa). Int J Epidemiol. 2006; 35(5):1146-50. DOI: 10.1093/ije/dyl170. View

15.

Hu F . The Mediterranean diet and mortality--olive oil and beyond. N Engl J Med. 2003; 348(26):2595-6. DOI: 10.1056/NEJMp030069. View

16.

Adamsson V, Reumark A, Fredriksson I, Hammarstrom E, Vessby B, Johansson G . Effects of a healthy Nordic diet on cardiovascular risk factors in hypercholesterolaemic subjects: a randomized controlled trial (NORDIET). J Intern Med. 2010; 269(2):150-9. DOI: 10.1111/j.1365-2796.2010.02290.x. View

17.

Bere E, Brug J . Towards health-promoting and environmentally friendly regional diets - a Nordic example. Public Health Nutr. 2008; 12(1):91-6. DOI: 10.1017/S1368980008001985. View

18.

Rogers L, Velten M . Maternal inflammation, growth retardation, and preterm birth: insights into adult cardiovascular disease. Life Sci. 2011; 89(13-14):417-21. DOI: 10.1016/j.lfs.2011.07.017. View

19.

Brantsaeter A, Haugen M, Alexander J, Meltzer H . Validity of a new food frequency questionnaire for pregnant women in the Norwegian Mother and Child Cohort Study (MoBa). Matern Child Nutr. 2008; 4(1):28-43. PMC: 6860878. DOI: 10.1111/j.1740-8709.2007.00103.x. View

20.

Klungsoyr K, Morken N, Irgens L, Vollset S, Skjaerven R . Secular trends in the epidemiology of pre-eclampsia throughout 40 years in Norway: prevalence, risk factors and perinatal survival. Paediatr Perinat Epidemiol. 2012; 26(3):190-8. DOI: 10.1111/j.1365-3016.2012.01260.x. View