» Articles » PMID: 25184061

Case Presentation - A Five-year Survival of the Patient with Glioblastoma Brain Tumor

Overview
Specialty Oncology
Date 2014 Sep 4
PMID 25184061
Citations 2
Authors
Affiliations
Soon will be listed here.
Abstract

This paper presents an atypical case of a patient with brain tumor of the glioblastoma multiforme (GBM) type who achieved a 5-year survival. Some general information is provided including epidemiology, diagnostic and treatment procedures (surgery and radio-chemo-therapy), and prognosis of survival related to GBM. The course of the disease, including its main symptoms, individual reasons for the delay of adjuvant treatment, after the primary surgical treatment, 37-month period of the decease free survival, as well as comprehensive management after the tumor recurrence are also presented. Histopathology confirming the clinical diagnosis is discussed in a separate chapter.

Citing Articles

Tumoricidal stem cell therapy enables killing in novel hybrid models of heterogeneous glioblastoma.

Satterlee A, Dunn D, Lo D, Khagi S, Hingtgen S Neuro Oncol. 2019; 21(12):1552-1564.

PMID: 31420675 PMC: 6917409. DOI: 10.1093/neuonc/noz138.


Metachronous medulloblastoma and glioblastoma: Implications for clinical and technical aspects of re-irradiation.

Verma V, Kulkarni R, Bhirud A, Bennion N, McComb R, Lin C Rep Pract Oncol Radiother. 2016; 21(1):84-9.

PMID: 26900364 PMC: 4716401. DOI: 10.1016/j.rpor.2015.10.002.

References
1.
van Meyel D, Ramsay D, Casson A, Keeney M, Chambers A, Cairncross J . p53 mutation, expression, and DNA ploidy in evolving gliomas: evidence for two pathways of progression. J Natl Cancer Inst. 1994; 86(13):1011-7. DOI: 10.1093/jnci/86.13.1011. View

2.
Hegi M, Diserens A, Gorlia T, Hamou M, De Tribolet N, Weller M . MGMT gene silencing and benefit from temozolomide in glioblastoma. N Engl J Med. 2005; 352(10):997-1003. DOI: 10.1056/NEJMoa043331. View

3.
Lang F, Miller D, Koslow M, Newcomb E . Pathways leading to glioblastoma multiforme: a molecular analysis of genetic alterations in 65 astrocytic tumors. J Neurosurg. 1994; 81(3):427-36. DOI: 10.3171/jns.1994.81.3.0427. View

4.
Simpson J, Horton J, Scott C, Curran W, Rubin P, Fischbach J . Influence of location and extent of surgical resection on survival of patients with glioblastoma multiforme: results of three consecutive Radiation Therapy Oncology Group (RTOG) clinical trials. Int J Radiat Oncol Biol Phys. 1993; 26(2):239-44. DOI: 10.1016/0360-3016(93)90203-8. View

5.
DeAngelis L . Anaplastic glioma: how to prognosticate outcome and choose a treatment strategy. [corrected]. J Clin Oncol. 2009; 27(35):5861-2. DOI: 10.1200/JCO.2009.24.5985. View