Failure of Mupirocin-resistant Staphylococci to Inactivate Mupirocin
Overview
Overview
Journal
Eur J Clin Microbiol Infect Dis
Publisher
Springer
Specialties
Infectious Diseases
Microbiology
Microbiology
Date
1989 Dec 1
PMID
2515962
Authors
Authors
Affiliations
Affiliations
Soon will be listed here.
Abstract
Isolates from four UK centres, comprising four Staphylococcus aureus strains and one Staphylococcus epidermidis strain with high-level mupirocin resistance, and one strain each of Staphylococcus aureus and Staphylococcus epidermidis with low-level mupirocin resistance, were assessed for intracellular or extracellular enzymatic alteration of the antibiotic. No change was seen in a number of assays, which included comparative disk diffusion, well diffusion and high-pressure liquid chromatography. Other mechanisms of resistance need to be explored in these isolates.
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