Alkaloids from the Tribe Bocconieae (papaveraceae): a Chemical and Biological Review

Overview

Journal Molecules

Publisher MDPI

Specialty Biology

Date 2014 Aug 27

PMID 25157468

Citations 9

Authors

Xuelong Yu

Xiaoli Gao

Zhixiang Zhu

Yuan Cao

Qian Zhang

Pengfei Tu

Xingyun Chai

Affiliations

Soon will be listed here.

Abstract

The Bocconieae tribe, consisting of only the genera Macleaya and Bocconia, possesses significant economic and medicinal value and plays an important role in health management for people in developing countries. During the past decades, research on metabolites and relative pharmacology, including the isolation and identification of a variety of molecules, has shed light on the tribe. Among those molecules, isoquinoline alkaloids, and their antimicrobial, antifungal, and anti-inflammatory activities are especially noteworthy. This paper presents a comprehensive compilation of current research progress, with emphasis on the alkaloids and their distribution, phytochemical and pharmacological investigation, toxicity and side effects, related chemotaxonomy and future use prospects, and hopefully provides a valuable reference as an effort to promote further exploration and application of this tribe.

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