So-eum Type As an Independent Risk Factor for Irritable Bowel Syndrome: a Population-based Study in Korea

Overview

Journal J Altern Complement Med

Specialty Rehabilitation Medicine

Date 2014 Aug 23

PMID 25148474

Citations 8

Authors

Seung Ku Lee

Dae Wui Yoon

Hyeryeon Yi

Si Woo Lee

Jong Yeol Kim

Jin Kwan Kim

Jeong Hwa Hong

Chol Shin

Affiliations

Soon will be listed here.

Abstract

Objectives: It has been hypothesized that Sasang constitutional types (SCTs) have a specific hypoactive organ, which can account for vulnerability to related diseases or symptoms. This study examined the relationship between SCTs and irritable bowel syndrome (IBS).

Design: Cross-sectional study in a population-based cohort study in Korea.

Participants: 1362 individuals (705 men and 657 women) who participated in the Korean Genome and Epidemiology Study.

Outcome Measures: The participants were classified into SCTs by the integrated diagnostic model and asked about symptoms related to IBS using the Rome II criteria.

Results: The prevalence of IBS differed significantly among the SCTs, with 33 (18.3%) of the So-eum (SE) type, 74 (9.9%) of the Tae-eum (TE) type, and 57 (13.2%) of the So-yang (SY) type having IBS. Even after adjustment for possible confounders, the SE type for both sexes continued to show 1.82-fold (95% confidence interval [CI], 1.05-3.16) excess odds of having IBS. Men with SE type had a 2.97 times (95% CI, 1.34-6.58) and a 2.50 times (95% CI, 1.15-5.47) significantly higher odds of having IBS than the TE and SY types, respectively. In analysis for the joint effect of SCT and psychological stress, the multivariate odds ratio of IBS was 3.21 (95% CI, 1.33-7.75) for the SE type and Psychological Well-Being Index-Short Form (PWI-SF) score (<27), and 5.83 (95% CI, 1.80-18.88) for the SE type and PWI-SF (≥27) compared with the TE type and PWI-SF score (<27).

Conclusions: The SE type of SCT is an independent risk factor for IBS. The findings support the hypothesis that persons with SE type are vulnerable to gastrointestinal diseases.

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References

Elsenbruch S, Thompson J, Hamish M, Exton M, Orr W . Behavioral and physiological sleep characteristics in women with irritable bowel syndrome. Am J Gastroenterol. 2002; 97(9):2306-14. DOI: 10.1111/j.1572-0241.2002.05984.x. View

Heitkemper M, Jarrett M, Jun S . Update on irritable bowel syndrome program of research. J Korean Acad Nurs. 2013; 43(5):579-86. DOI: 10.4040/jkan.2013.43.5.579. View

Ranjbaran Z, Keefer L, Farhadi A, Stepanski E, Sedghi S, Keshavarzian A . Impact of sleep disturbances in inflammatory bowel disease. J Gastroenterol Hepatol. 2007; 22(11):1748-53. DOI: 10.1111/j.1440-1746.2006.04820.x. View

Baracos V . Hypercatabolism and hypermetabolism in wasting states. Curr Opin Clin Nutr Metab Care. 2002; 5(3):237-9. DOI: 10.1097/00075197-200205000-00001. View

El-Salhy M . Irritable bowel syndrome: diagnosis and pathogenesis. World J Gastroenterol. 2012; 18(37):5151-63. PMC: 3468846. DOI: 10.3748/wjg.v18.i37.5151. View

Manning A, Thompson W, Heaton K, Morris A . Towards positive diagnosis of the irritable bowel. Br Med J. 1978; 2(6138):653-4. PMC: 1607467. DOI: 10.1136/bmj.2.6138.653. View

Longstreth G, Grant Thompson W, Chey W, Houghton L, Mearin F, Spiller R . Functional bowel disorders. Gastroenterology. 2006; 130(5):1480-91. DOI: 10.1053/j.gastro.2005.11.061. View

Lee T, Koh B, Lee S . Sasang constitution as a risk factor for diabetes mellitus: a cross-sectional study. Evid Based Complement Alternat Med. 2009; 6 Suppl 1:99-103. PMC: 2741626. DOI: 10.1093/ecam/nep054. View

Floch M . Use of diet and probiotic therapy in the irritable bowel syndrome: analysis of the literature. J Clin Gastroenterol. 2005; 39(5 Suppl 3):S243-6. DOI: 10.1097/01.mcg.0000156104.67505.5b. View

10.

Tan Y, Goh K, Muhidayah R, Ooi C, Salem O . Prevalence of irritable bowel syndrome in young adult Malaysians: a survey among medical students. J Gastroenterol Hepatol. 2003; 18(12):1412-6. DOI: 10.1046/j.1440-1746.2003.03212.x. View

11.

Kearney D, Brown-Chang J . Complementary and alternative medicine for IBS in adults: mind-body interventions. Nat Clin Pract Gastroenterol Hepatol. 2008; 5(11):624-36. DOI: 10.1038/ncpgasthep1257. View

12.

Harvey R, Salih S, Read A . Organic and functional disorders in 2000 gastroenterology outpatients. Lancet. 1983; 1(8325):632-4. DOI: 10.1016/s0140-6736(83)91802-0. View

13.

Visser M, Bouter L, McQuillan G, Wener M, Harris T . Elevated C-reactive protein levels in overweight and obese adults. JAMA. 1999; 282(22):2131-5. DOI: 10.1001/jama.282.22.2131. View

14.

Beck A, Ward C, Mendelson M, Mock J, ERBAUGH J . An inventory for measuring depression. Arch Gen Psychiatry. 1961; 4:561-71. DOI: 10.1001/archpsyc.1961.01710120031004. View

15.

Lee M, Sohn K, Kim Y, Hwang M, Kwon Y, Bae N . Digestive system-related pathophysiological symptoms of Sasang typology: Systematic review. Integr Med Res. 2017; 2(2):39-48. PMC: 5481684. DOI: 10.1016/j.imr.2013.04.001. View

16.

Sperber A, Drossman D . Irritable bowel syndrome: a multidimensional disorder cannot be understood or treated from a unidimensional perspective. Therap Adv Gastroenterol. 2012; 5(6):387-93. PMC: 3491682. DOI: 10.1177/1756283X12460420. View

17.

McEwen B, Wingfield J . The concept of allostasis in biology and biomedicine. Horm Behav. 2003; 43(1):2-15. DOI: 10.1016/s0018-506x(02)00024-7. View

18.

Rhee P . [Definition and epidemiology of irritable bowel syndrome]. Korean J Gastroenterol. 2006; 47(2):94-100. View

19.

Do J, Jang E, Ku B, Jang J, Kim H, Kim J . Development of an integrated Sasang constitution diagnosis method using face, body shape, voice, and questionnaire information. BMC Complement Altern Med. 2012; 12:85. PMC: 3502327. DOI: 10.1186/1472-6882-12-85. View

20.

Lee J, Lee J, Lee E, Yoo J, Kim Y, Koh B . The Sasang constitutional types can act as a risk factor for hypertension. Clin Exp Hypertens. 2011; 33(8):525-32. DOI: 10.3109/10641963.2011.561901. View