Quality of Life After Pulmonary Embolism: First Cross-cultural Evaluation of the Pulmonary Embolism Quality-of-life (PEmb-QoL) Questionnaire in a Norwegian Cohort

Overview

Journal Qual Life Res

Specialties Pharmacology
Rehabilitation Medicine

Date 2014 Aug 15

PMID 25120017

Citations 8

Authors

Mazdak Tavoly

Lars-Petter Jelsness-Jorgensen

Hilde Skuterud Wik

Christina Roaldsnes

Per Morten Sandset

Waleed Ghanima

Affiliations

Soon will be listed here.

Abstract

Purpose: The aim of the current study was to translate and test the psychometrical properties of the disease-specific pulmonary embolism quality-of-life questionnaire (PEmb-QoL).

Methods: Patients with a prior history of pulmonary embolism (PE) were identified from the thrombosis registry at Østfold Hospital Trust, Fredrikstad, Norway. All eligible patients were asked to complete the generic EuroQol 5-dimension (EQ-5D) QoL questionnaire as well as the disease-specific PEmb-QoL at baseline and after 2 weeks. Construct validity was tested using principal component factor analysis. Criterion validity was tested using Spearman's correlation coefficients (rho) between EQ-5D and PEmb-QoL. Internal consistency reliability was calculated using Cronbach's alpha coefficient, while test-retest reliability was calculated using the intra-class correlation coefficients (ICC).

Results: A total of 213 participants had complete datasets and were included in further analyses. Factor analysis with varimax rotation yielded six factors explaining 71% of the cumulative variance. Cronbach's alpha coefficient was found to be 0.94, indicating a very good intercorrelation of items. Of the 213 participants, 145 (68%) completed the questionnaire a second time. The ICC ranged from 0.75 to 0.86, indicating good test-retest reliability. All factors were found significant with p values <0.001. The criterion validity of the PEmb-QoL was confirmed through good correlation with other similar health-related quality-of-life constructs in the EQ-5D.

Conclusions: Findings of the current study indicate that Norwegian version of the PEmb-QoL is both valid and reliable, thus representing an important supplement in subjective outcomes measurement among patients sustaining PE.

Citing Articles

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Cross-cultural validity of the Pulmonary Embolism Quality of Life questionnaire in the quality of life survey after pulmonary embolism: A Persian-speaking cohort.

Mehdizadeh K, Mohseni Salehi M, Moosavi J, Mohebbi B, Klok F, Bikdeli B Res Pract Thromb Haemost. 2023; 7(3):100145.

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Assessing quality of life after pulmonary embolism: Comparing results from the PEmb-QoL with semistructured interviews.

Hernandez-Nino J, Ott M, Thomas M, Alexander A, Kline J Res Pract Thromb Haemost. 2022; 6(4):e12732.

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Rolving N, Brocki B, Bloch-Nielsen J, Larsen T, Jensen F, Mikkelsen H JAMA Netw Open. 2020; 3(2):e200064.

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Quality of life and functional limitations after pulmonary embolism and its prognostic relevance.

Keller K, Tesche C, Gerhold-Ay A, Nickels S, Klok F, Rappold L J Thromb Haemost. 2019; 17(11):1923-1934.

PMID: 31344319 PMC: 6900046. DOI: 10.1111/jth.14589.

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