[Clinical Features and Prurigo Nodularis in Nephrogenic Pruritus]

Overview

Journal Hautarzt

Specialty Dermatology

Date 2014 Aug 13

PMID 25113331

Citations 4

Authors

T Bohme

T Heitkemper

T Mettang

N Q Phan

S Stander

Affiliations

Soon will be listed here.

Abstract

Background: Nephrogenic pruritus (NP) is a well-known associated symptom in patients with chronic renal failure. The aim of the present study was to make a detailed dermatological analysis including distribution of excoriations and their correlation with pruritus characteristics.

Patients And Methods: Data on a total of 17 patients with NP (14 males, mean 65.4 ± SD 14.3 years) were subjected to retrospective analysis. Most of the patients developed NP after start of kidney disease; however, in 20 % of the patients, there was premonitory appearance of the symptom 18 months (median) earlier. A majority of patients reported neuropathic symptom qualities (burning, stinging). In 94.1 % of patients xerosis was present; in 58.8 %, prurigo nodularis. The latter group of patients had a longer duration of pruritus as well as up to 10 years longer duration of renal disease than those without prurigo.

Results: Pruritus characteristics of NP show a wide variance without a clear profile that is useful for clinical diagnosis. NP can occur premonitorily, and, if of long duration and with coexistent metabolic diseases, can develop into prurigo.

Citing Articles

Impact of Chronic Kidney Disease Severity on the Risk of Prurigo Nodularis: A Population-Based Cohort Study.

Kim H, Kim H, Ahn H Acta Derm Venereol. 2022; 102:adv00781.

PMID: 35971831 PMC: 9677257. DOI: 10.2340/actadv.v102.2227.

Diagnostic Workup and Evaluation of Patients with Prurigo Nodularis.

Kwon C, Khanna R, Williams K, Kwatra M, Kwatra S Medicines (Basel). 2019; 6(4).

PMID: 31561504 PMC: 6963711. DOI: 10.3390/medicines6040097.

[84-year-old female with generalized chronic pruritus on unchanged skin : Preparation for the specialist examination: part 29].

Hoffmann V, Stander S Hautarzt. 2019; 70(Suppl 1):11-15.

PMID: 30976853 DOI: 10.1007/s00105-018-4321-4.

[Chronic prurigo].

Pereira M, Nau T, Zeidler C, Stander S Hautarzt. 2018; 69(4):321-330.

PMID: 29568995 DOI: 10.1007/s00105-018-4145-2.

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