Surgical Resection or Aspiration with Ethanol Sclerotherapy of Endometrioma Before in Vitro Fertilization in Infertilie Women with Endometrioma

Overview

Journal Obstet Gynecol Sci

Specialty Gynecology & Obstetrics

Date 2014 Aug 9

PMID 25105103

Citations 15

Authors

Kyung-Hee Lee

Chung-Hoon Kim

You-Jeong Lee

Sung-Hoon Kim

Hee-Dong Chae

Byung-Moon Kang

Affiliations

Soon will be listed here.

Abstract

Objective: To evaluate whether the surgical resection or aspiration with ethanol sclerotherapy (AEST) of endometrioma before in vitro fertilization (IVF) affect controlled ovarian stimulation (COS) and IVF outcome in the infertilie women with endometroma undergoing IVF.

Methods: In this retrospective cohort study, 101 consecutive IVF/intracytoplasmic sperm injection cycles that were performed in 101 patients with endometrioma(s) between January 2008 and December 2012 were included. Before IVF, 36 patients underwent surgical resection of endometrioma (resection group), 29 patients had transvaginal endometrioma AEST (aspiration group), and 36 patients did not take any surgical intervention (control group). The three groups were compared in terms of COS and IVF outcomes.

Results: Total antral follicle count was significantly lower in the resection group than in the aspiration or control group. The numbers of follicles with a diameter of 14 to 17 mm on the human chorionic gonadotropin day, retrieved oocytes, mature oocytes, and fertilized oocytes were significantly lower in the resection group than in two other groups. However, three groups were similar in terms of clinical pregnancy rate (CPR) per initiated cycle, CPR per embryo transfer, embryo implantation rate, and miscarriage rate.

Conclusion: Neither of surgical resection and AEST of endometrioma before IVF treatment can give any beneficial effect on IVF outcomes. Moreover, surgical resection of endometrioma can affect the ovarian reserve and ovarian response during COS.

Citing Articles

Ethanol Sclerotherapy for Endometriomas in Infertile Women: A Narrative Review.

Sukur Y, Aslan B, Varli B, Ozcan P, Daniilidis A, Kalaitzopoulos D J Clin Med. 2025; 13(24.

PMID: 39768471 PMC: 11727901. DOI: 10.3390/jcm13247548.

Comparison of Surgical Interventions for Endometrioma: A Systematic Review of Their Efficacy in Addressing Infertility.

Ioannidou A, Machairiotis N, Stavros S, Potiris A, Karampitsakos T, Pantelis A Biomedicines. 2025; 12(12.

PMID: 39767836 PMC: 11672971. DOI: 10.3390/biomedicines12122930.

Ethanol Sclerotherapy in the Management of Ovarian Endometrioma: Technical Considerations for Catheter- and Needle-Directed Sclerotherapy.

Azizova A, Ciftci T, Gultekin M, Unal E, Akhan O, Bozdag G Cardiovasc Intervent Radiol. 2024; 47(7):891-900.

PMID: 38551784 PMC: 11239738. DOI: 10.1007/s00270-024-03694-0.

The Efficacy and Safety of Transvaginal Ethanol Sclerotherapy in the Treatment of Endometrial Cysts-A Systematic Review.

Frankowska K, Dymanowska-Dyjak I, Abramiuk M, Polak G Int J Mol Sci. 2024; 25(2).

PMID: 38279336 PMC: 10816543. DOI: 10.3390/ijms25021337.

Endometriosis: An Overview.

Agnihotri T, Ghosh A, Lamba A, Ray Jr C Semin Intervent Radiol. 2024; 40(6):544-548.

PMID: 38274215 PMC: 10807967. DOI: 10.1055/s-0043-1777748.

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