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Bilateral Choroidal Osteoma with Choroidal Neovascular Membrane Treated with Bevacizumab in a Child

Overview
Specialty Ophthalmology
Date 2014 Aug 8
PMID 25100914
Citations 3
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Abstract

Choroidal osteoma is a rare benign tumor. We report a male child diagnosed with bilateral choroidal osteoma, high myopia and secondary choroidal neovascularization (CNV) membrane in one eye. Co-existence of posterior staphyloma made the clinical diagnosis of choroidal osteoma difficult due to the osteoma filling the depression of the posterior staphyloma. Typical findings on fundus fluorescein angiography, optical coherence tomography, B-scan and indocyanine green angiography confirmed the diagnosis. A review of literature was performed. CNV secondary to choroidal osteoma was treated with intravitreal bevacizumab and it responded well. Regular follow-up is essential for recurrence of CNV and decalcification of the osteoma.

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References
1.
Battaglia Parodi M, Da Pozzo S, Toto L, Saviano S, Ravalico G . Photodynamic therapy for choroidal neovascularization associated with choroidal osteoma. Retina. 2002; 21(6):660-1. DOI: 10.1097/00006982-200112000-00016. View

2.
Foster B, Fernandez-Suntay J, Dryja T, Jakobiec F, DAmico D . Clinicopathologic reports, case reports, and small case series: surgical removal and histopathologic findings of a subfoveal neovascular membrane associated with choroidal osteoma. Arch Ophthalmol. 2003; 121(2):273-6. DOI: 10.1001/archopht.121.2.273. View

3.
Aylward G, Chang T, Pautler S, GASS J . A long-term follow-up of choroidal osteoma. Arch Ophthalmol. 1998; 116(10):1337-41. DOI: 10.1001/archopht.116.10.1337. View

4.
Song W, Koh H, Kwon O, Byeon S, Lee S . Intravitreal bevacizumab for choroidal neovascularization secondary to choroidal osteoma. Acta Ophthalmol. 2009; 87(1):100-1. DOI: 10.1111/j.1600-0420.2007.01136.x. View

5.
Ahmadieh H, Vafi N . Dramatic response of choroidal neovascularization associated with choroidal osteoma to the intravitreal injection of bevacizumab (Avastin). Graefes Arch Clin Exp Ophthalmol. 2007; 245(11):1731-3. DOI: 10.1007/s00417-007-0636-z. View