Body Mass Index and Response to a Multidisciplinary Treatment of Fibromyalgia

Overview

Journal Rheumatol Int

Specialty Rheumatology

Date 2014 Aug 2

PMID 25080875

Citations 6

Authors

Antoni Castel

Sonia Castro

Ramon Fontova

Maria Jose Poveda

Rosalia Cascon-Pereira

Salvador Montull

Anna Padrol

Rami Qanneta

Maria Rull

Affiliations

Soon will be listed here.

Abstract

The purpose of this study is to determine whether there are some differences in the treatment responses to a multidisciplinary fibromyalgia (FM) treatment related with the baseline body mass index (BMI) of the participants. Inclusion criteria consisted of female sex, a diagnosis of FM (American College of Rheumatology criteria), age between 18 and 60 years, and between 3 and 8 years of schooling. Baseline BMI was determined, and patients were randomly assigned to one of the two treatment conditions: conventional pharmacologic treatment or multidisciplinary treatment. Outcome measures were pain intensity, functionality, catastrophizing, psychological distress, health-related quality of life, and sleep disturbances. One hundred thirty patients participated in the study. No statistical significant differences regarding pre-treatment outcomes were found among the different BMI subgroups, and between the two experimental conditions for each BMI category. General linear model analysis showed a significant interaction group treatment × time in pain intensity (p < .01), functionality (p < .0001), catastrophizing (p < .01), psychological distress (p < .0001), sleep index problems (p < .0001), and health-related quality of life (p < .05). No significant interactions were found in BMI × time, and in BMI × group treatment × time. There are not differences among normal weight, overweight and obese patients with FM regarding their response to a multidisciplinary treatment programme for FM which combines pharmacological treatment, education, physical therapy and cognitive behavioural therapy.

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References

Janke E, Collins A, Kozak A . Overview of the relationship between pain and obesity: What do we know? Where do we go next?. J Rehabil Res Dev. 2007; 44(2):245-62. DOI: 10.1682/jrrd.2006.06.0060. View

Kim C, Luedtke C, Vincent A, Thompson J, Oh T . Association of body mass index with symptom severity and quality of life in patients with fibromyalgia. Arthritis Care Res (Hoboken). 2011; 64(2):222-8. DOI: 10.1002/acr.20653. View

Altan L, Bingol U, Aykac M, Koc Z, Yurtkuran M . Investigation of the effects of pool-based exercise on fibromyalgia syndrome. Rheumatol Int. 2003; 24(5):272-7. DOI: 10.1007/s00296-003-0371-7. View

White K, Speechley M, Harth M, Ostbye T . The London Fibromyalgia Epidemiology Study: the prevalence of fibromyalgia syndrome in London, Ontario. J Rheumatol. 1999; 26(7):1570-6. View

Bernardy K, Fuber N, Kollner V, Hauser W . Efficacy of cognitive-behavioral therapies in fibromyalgia syndrome - a systematic review and metaanalysis of randomized controlled trials. J Rheumatol. 2010; 37(10):1991-2005. DOI: 10.3899/jrheum.100104. View

Timmerman G, Calfa N, Stuifbergen A . Correlates of body mass index in women with fibromyalgia. Orthop Nurs. 2013; 32(2):113-9. PMC: 3616378. DOI: 10.1097/NOR.0b013e3182879c08. View

Yunus M, Arslan S, Aldag J . Relationship between body mass index and fibromyalgia features. Scand J Rheumatol. 2002; 31(1):27-31. DOI: 10.1080/030097402317255336. View

Zigmond A, SNAITH R . The hospital anxiety and depression scale. Acta Psychiatr Scand. 1983; 67(6):361-70. DOI: 10.1111/j.1600-0447.1983.tb09716.x. View

Oh T, Hoskin T, Luedtke C, Weingarten T, Vincent A, Kim C . Predictors of clinical outcome in fibromyalgia after a brief interdisciplinary fibromyalgia treatment program: single center experience. PM R. 2012; 4(4):257-63. DOI: 10.1016/j.pmrj.2011.10.014. View

10.

Farrar J, Young Jr J, Lamoreaux L, Werth J, Poole M . Clinical importance of changes in chronic pain intensity measured on an 11-point numerical pain rating scale. Pain. 2001; 94(2):149-158. DOI: 10.1016/S0304-3959(01)00349-9. View

11.

Mork P, Vasseljen O, Nilsen T . Association between physical exercise, body mass index, and risk of fibromyalgia: longitudinal data from the Norwegian Nord-Trøndelag Health Study. Arthritis Care Res (Hoboken). 2010; 62(5):611-7. DOI: 10.1002/acr.20118. View

12.

Rosenstiel A, Keefe F . The use of coping strategies in chronic low back pain patients: relationship to patient characteristics and current adjustment. Pain. 1983; 17(1):33-44. DOI: 10.1016/0304-3959(83)90125-2. View

13.

Dolores Arenas M, Alvarez-Ude F, Reig-Ferrer A, Zito J, Gil M, Carreton M . Emotional distress and health-related quality of life in patients on hemodialysis: the clinical value of COOP-WONCA charts. J Nephrol. 2007; 20(3):304-10. View

14.

Arranz L, Canela M, Rafecas M . Relationship between body mass index, fat mass and lean mass with SF-36 quality of life scores in a group of fibromyalgia patients. Rheumatol Int. 2011; 32(11):3605-11. DOI: 10.1007/s00296-011-2250-y. View

15.

Branco J, Bannwarth B, Failde I, Abello Carbonell J, Blotman F, Spaeth M . Prevalence of fibromyalgia: a survey in five European countries. Semin Arthritis Rheum. 2009; 39(6):448-53. DOI: 10.1016/j.semarthrit.2008.12.003. View

16.

Hauser W, Bernardy K, Arnold B, Offenbacher M, Schiltenwolf M . Efficacy of multicomponent treatment in fibromyalgia syndrome: a meta-analysis of randomized controlled clinical trials. Arthritis Rheum. 2009; 61(2):216-24. DOI: 10.1002/art.24276. View

17.

Burckhardt C, Clark S, Bennett R . The fibromyalgia impact questionnaire: development and validation. J Rheumatol. 1991; 18(5):728-33. View

18.

Morales Garcia A, Arenas Jimenez M, Reig-Ferrer A, Alvarez-Ude F, Malek T, Moledous A . [Dispositional optimism in patients on chronic haemodialysis and its possible influence on their clinical course]. Nefrologia. 2011; 31(2):199-205. DOI: 10.3265/Nefrologia.pre2011.Feb.10534. View

19.

Jensen M, Turner J, Romano J, Fisher L . Comparative reliability and validity of chronic pain intensity measures. Pain. 1999; 83(2):157-62. DOI: 10.1016/s0304-3959(99)00101-3. View

20.

Bannwarth B, Blotman F, Roue-Le Lay K, Caubere J, Andre E, Taieb C . Fibromyalgia syndrome in the general population of France: a prevalence study. Joint Bone Spine. 2008; 76(2):184-7. DOI: 10.1016/j.jbspin.2008.06.002. View